Mesenchymal stromal cell therapy for liver diseases

M Alfaifi, YW Eom, PN Newsome, SK Baik - Journal of hepatology, 2018 - Elsevier
The therapeutic potential of mesenchymal stromal cells (MSCs) in the treatment of liver
fibrosis is predominantly based on their immunosuppressive properties, and their ability to …

Characteristics and therapeutic potential of human amnion-derived stem cells

QW Liu, QM Huang, HY Wu, GSL Zuo, HC Gu… - International journal of …, 2021 - mdpi.com
Stem cells including embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs)
and adult stem cells (ASCs) are able to repair/replace damaged or degenerative tissues and …

Recent development in therapeutic cardiac patches

X Mei, K Cheng - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
For the past decades, heart diseases remain the leading cause of death worldwide. In the
adult mammalian heart, damaged cardiomyocytes will be replaced by non-contractile fibrotic …

Stem cell therapies for chronic liver diseases: progress and challenges

TT Li, ZR Wang, WQ Yao, EQ Linghu… - Stem Cells …, 2022 - academic.oup.com
Chronic liver diseases have become a significant health issue worldwide and urgently
require the development of novel therapeutic approaches, in addition to liver transplantation …

Amniotic membrane-mesenchymal stromal cells secreted factors and extracellular vesicle-miRNAs: Anti-inflammatory and regenerative features for musculoskeletal …

E Ragni, A Papait, C Perucca Orfei… - Stem Cells …, 2021 - academic.oup.com
Human amniotic membrane-derived mesenchymal stromal cells (hAMSCs) are easily
obtained in large quantities and free from ethical concerns. Promising therapeutic results for …

The immunomodulatory properties of amniotic cells: the two sides of the coin

M Magatti, E Vertua, A Cargnoni, A Silini… - Cell …, 2018 - journals.sagepub.com
Among the many cell types useful in developing therapeutic treatments, human amniotic
cells from placenta have been proposed as valid candidates. Both human amniotic epithelial …

Comparison of EV-free fraction, EVs, and total secretome of amniotic mesenchymal stromal cells for their immunomodulatory potential: A translational perspective

A Papait, E Ragni, A Cargnoni, E Vertua… - Frontiers in …, 2022 - frontiersin.org
Amniotic mesenchymal stromal cells (hAMSCs) have unique immunomodulatory properties
demonstrated in vitro and in vivo in various diseases in which the dysregulated immune …

Human amniotic membrane and amniotic membrane–derived cells: how far are we from their use in regenerative and reconstructive urology?

TŽ Ramuta, ME Kreft - Cell transplantation, 2018 - journals.sagepub.com
Human amniotic membrane (hAM) is the innermost layer of fetal membranes, which
surrounds the developing fetus and forms the amniotic cavity. hAM and hAM-derived cells …

Amniotic membrane and its derivatives: novel therapeutic modalities in liver disorders

MK Arki, K Moeinabadi-Bidgoli, N Hossein-Khannazer… - Cells, 2023 - mdpi.com
The liver is a vital organ responsible for metabolic and digestive functions, protein synthesis,
detoxification, and numerous other necessary functions. Various acute, chronic, and …

B lymphocytes as targets of the immunomodulatory properties of human amniotic mesenchymal stromal cells

M Magatti, A Masserdotti, P Bonassi Signoroni… - Frontiers in …, 2020 - frontiersin.org
Mesenchymal stromal cells (MSC) from the amniotic membrane of human term placenta
(hAMSC), and the conditioned medium generated from their culture (CM-hAMSC) offer …