Comparing HIV‐1 and HIV‐2 infection: Lessons for viral immunopathogenesis

S Nyamweya, A Hegedus, A Jaye… - Reviews in medical …, 2013 - Wiley Online Library
SUMMARY HIV‐1 and HIV‐2 share many similarities including their basic gene
arrangement, modes of transmission, intracellular replication pathways and clinical …

Antiretroviral therapy and drug resistance in human immunodeficiency virus type 2 infection

L Menéndez-Arias, M Álvarez - Antiviral research, 2014 - Elsevier
One to two million people worldwide are infected with the human immunodeficiency virus
type 2 (HIV-2), with highest prevalences in West African countries, but also present in …

Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape

KJ Bar, C Tsao, SS Iyer, JM Decker, Y Yang… - PLoS …, 2012 - journals.plos.org
Single genome sequencing of early HIV-1 genomes provides a sensitive, dynamic
assessment of virus evolution and insight into the earliest anti-viral immune responses in …

Comparison of antibody-dependent cell-mediated cytotoxicity and virus neutralization by HIV-1 Env-specific monoclonal antibodies

B von Bredow, JF Arias, LN Heyer, B Moldt… - Journal of …, 2016 - Am Soc Microbiol
Although antibodies to the human immunodeficiency virus type 1 (HIV-1) envelope
glycoprotein have been studied extensively for their ability to block viral infectivity, little data …

Virological features associated with the development of broadly neutralizing antibodies to HIV-1

PL Moore, C Williamson, L Morris - Trends in microbiology, 2015 - cell.com
The development of a preventative HIV-1 vaccine remains a global public health priority.
This will likely require the elicitation of broadly neutralizing antibodies (bNAbs) able to block …

Targeted isolation of antibodies directed against major sites of SIV Env vulnerability

RD Mason, HC Welles, C Adams… - PLoS …, 2016 - journals.plos.org
The simian immunodeficiency virus (SIV) challenge model of lentiviral infection is often used
as a model to human immunodeficiency virus type 1 (HIV-1) for studying vaccine mediated …

HIV-2 as a model to identify a functional HIV cure

J Esbjörnsson, M Jansson, S Jespersen… - AIDS research and …, 2019 - Springer
Two HIV virus types exist: HIV-1 is pandemic and aggressive, whereas HIV-2 is confined
mainly to West Africa and less pathogenic. Despite the fact that it has been almost 40 years …

[PDF][PDF] HIV Interaction With Human Host: HIV-2 As a Model of a Less Virulent Infection.

JM Azevedo-Pereira, Q Santos-Costa - AIDS reviews, 2016 - researchgate.net
Abstract HIV-1 and HIV-2 are the causal agents of AIDS. While similar in many ways, a
significant amount of data suggests that HIV-2 is less virulent than HIV-1. In fact, HIV-2 …

Antibody-dependent cellular cytotoxicity, infected cell binding and neutralization by antibodies to the SIV envelope glycoprotein

MW Grunst, RA Ladd, NM Clark, HM Gil… - PLoS …, 2023 - journals.plos.org
Antibodies specific for diverse epitopes of the simian immunodeficiency virus envelope
glycoprotein (SIV Env) have been isolated from rhesus macaques to provide physiologically …

A high prevalence of potential HIV elite controllers identified over 30 years in Democratic Republic of Congo

MG Berg, A Olivo, BJ Harris, MA Rodgers, L James… - …, 2021 - thelancet.com
Background In-depth analysis of the HIV pandemic at its epicenter in the Congo basin has
been hampered by 40 years of political unrest and lack of functional public health …