5-Fluorouracil nano-delivery systems as a cutting-edge for cancer therapy
Fluorouracil (5-FU) is amongst the most commonly used antimetabolite chemotherapeutic
agents in recent decades. However, its low bioavailability, short half-life, rapid metabolism …
agents in recent decades. However, its low bioavailability, short half-life, rapid metabolism …
Nanomaterials as an advanced nano-tool for the doxorubicin delivery/Co-Delivery—A comprehensive review
Cancer is the deadliest multifactorial disease, constituting variations at the molecular and
histological level. Cancer is being treated on advanced step via utilization of the multiple …
histological level. Cancer is being treated on advanced step via utilization of the multiple …
Multifunctional nanocomposites integrated green synthesized amphiphilic chitosan/thyme extract/nanosilver for antimicrobial and anti-biofilm applications
Background Bacterial biofilms pose a significant challenge in various industries, including
healthcare and food production, as they can lead to persistent infections, antibiotic …
healthcare and food production, as they can lead to persistent infections, antibiotic …
Examining the quaternary ammonium chitosan Schiff base-ZnO nanocomposite's potential as protective therapy for rats' cisplatin-induced hepatotoxicity
ES Kotb, HW Alhamdi, MY Alfaifi, O Darweesh… - International Journal of …, 2024 - Elsevier
Background Despite cisplatin's long history as a cornerstone in cancer therapy, both
acquired chemoresistance and significant impacts on healthy tissues limit its use …
acquired chemoresistance and significant impacts on healthy tissues limit its use …
Functionalized imidazolium ionic liquids-modified chitosan materials: From synthesis approaches to applications
NF Alqahtani - Reactive and Functional Polymers, 2024 - Elsevier
Biodegradability, biocompatibility, and biological activity are just a few of the unique
qualities of chitosan, a biopolymer produced from chitin, that have garnered widespread …
qualities of chitosan, a biopolymer produced from chitin, that have garnered widespread …
Recent advances in the development of chitosan/hyaluronic acid-based hybrid materials for skin protection, regeneration, and healing: A review
J Alkabli - International Journal of Biological Macromolecules, 2024 - Elsevier
Biomaterials play vital roles in regenerative medicine, specifically in tissue engineering
applications. They promote angiogenesis and facilitate tissue creation and repair. The most …
applications. They promote angiogenesis and facilitate tissue creation and repair. The most …
Harnessing folate-functionalized nasal delivery of dox–erlo-loaded biopolymeric nanoparticles in cancer treatment: development, optimization, characterization, and …
The aim of the present study is to develop Doxorubicin–Erlotinib nanoparticles (Dox–Erlo
NPs) and folate-armored Dox–Erlo-NP conjugates for targeting glioma cancer. Glioma is …
NPs) and folate-armored Dox–Erlo-NP conjugates for targeting glioma cancer. Glioma is …
Alginate-chitosan-microencapsulated tyrosols/oleuropein-rich olive mill waste extract for lipopolysaccharide-induced skin fibroblast inflammation treatment
The Ca 2+ ion-driven emulsification-ionotropic gelation method produced chitosan-alginate
microspheres (CAMSs) with a narrow particle size distribution (PSD). Particle size …
microspheres (CAMSs) with a narrow particle size distribution (PSD). Particle size …
Quercetin and 5-Fu Loaded Chitosan Nanoparticles Trigger Cell-Cycle Arrest and Induce Apoptosis in HCT116 Cells via Modulation of the P53/P21 Axis
Nanoparticles (NPs) are encapsulating agents that exist in the nanometer range. They can
be classified into different classes based on their properties, shapes, or sizes. Metal NPs …
be classified into different classes based on their properties, shapes, or sizes. Metal NPs …
Cross-linked quaternized chitosan nanoparticles for effective delivery and controllable release of O. europaea phenolic extract targeting cancer therapy
Although current therapies for cancer patients have saved many lives, finding more effective
remedies is still a challenge. To that end, we have begun to explore the potential of cross …
remedies is still a challenge. To that end, we have begun to explore the potential of cross …