Effect of estrous cycle on behavior of females in rodent tests of anxiety

TA Lovick, H Zangrossi Jr - Frontiers in psychiatry, 2021 - frontiersin.org
Anxiety disorders are more prevalent in women than in men. In women the menstrual cycle
introduces another variable; indeed, some conditions eg, premenstrual syndrome, are …

A fear conditioned cue orchestrates a suite of behaviors in rats

A Chu, NT Gordon, AM DuBois, CB Michel… - Elife, 2024 - elifesciences.org
Pavlovian fear conditioning has been extensively used to study the behavioral and neural
basis of defensive systems. In a typical procedure, a cue is paired with foot shock, and …

Defensive and emotional behavior modulation by serotonin in the periaqueductal gray

P Vázquez-León, A Miranda-Páez… - Cellular and Molecular …, 2023 - Springer
Abstract Serotonin 5-hydroxytryptamine (5-HT) is a key neurotransmitter for the modulation
and/or regulation of numerous physiological processes and psychiatric disorders (eg …

[HTML][HTML] Functional neuroanatomy in panic disorder: Status quo of the research

T Sobanski, G Wagner - World journal of psychiatry, 2017 - ncbi.nlm.nih.gov
AIM To provide an overview of the current research in the functional neuroanatomy of panic
disorder. METHODS Panic disorder (PD) is a frequent psychiatric disease. Gorman et al …

CB1 receptor signalling mediates cannabidiol-induced panicolytic-like effects and defensive antinociception impairment in mice threatened by Bothrops jararaca …

BM de Paula Rodrigues… - Journal of …, 2022 - journals.sagepub.com
Background: Cannabis sativa-derived substances such as cannabidiol (CBD) have attracted
increasing clinical interest and consist in a new perspective for treating some neurological …

Neural Control of Naturalistic Behavior Choices

SK Asinof, GM Card - Annual Review of Neuroscience, 2024 - annualreviews.org
In the natural world, animals make decisions on an ongoing basis, continuously selecting
which action to undertake next. In the lab, however, the neural bases of decision processes …

[HTML][HTML] Panic-like escape response elicited in mice by exposure to CO2, but not hypoxia

A Spiacci Jr, HH Vilela-Costa, AB Sant'Ana… - Progress in Neuro …, 2018 - Elsevier
Exposure to elevated concentrations of CO 2 or hypoxia has been widely used in psychiatric
research as a panic provoking stimulus. However, the use of these respiratory challenges to …

Translational approach to the pathophysiology of panic disorder: Focus on serotonin and endogenous opioids

FG Graeff - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Panic patients experience recurrent panic attacks. Two main neurochemical hypotheses
have been proposed to explain this vulnerability. The first suggests that panic patients have …

Connexions between the dorsomedial division of the ventromedial hypothalamus and the dorsal periaqueductal grey matter are critical in the elaboration of …

F Ullah, T dos Anjos-Garcia, J Mendes-Gomes… - Behavioural Brain …, 2017 - Elsevier
The electrical and chemical stimulation of the dorsal periaqueductal grey matter (dPAG)
elicits panic-like explosive escape behaviour. Although neurons of the ventromedial …

Psychedelics: A review of their effects on recalled aversive memories and fear/anxiety expression in rodents

I Werle, LJ Bertoglio - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Threatening events and stressful experiences can lead to maladaptive memories and
related behaviors. Existing treatments often fail to address these issues linked to …