Specialized Pulmonary Vascular Cells in Development and Disease

A Sharma, TK Niethamer - Annual Review of Physiology, 2024 - annualreviews.org
Endothelial cells (ECs) develop organ-specific gene expression and function in response to
signals from the surrounding tissue. In turn, ECs can affect organ development and …

Recent progress in neonatal hyperoxic lung injury

T Rao, Y Zhou, C Chen, J Chen, J Zhang… - Pediatric …, 2024 - Wiley Online Library
With the progress in neonatal intensive care, there has been an increase in the survival
rates of premature infants. However, this has also led to an increased incidence of neonatal …

BMAL1 sex‐specific effects in the neonatal mouse airway exposed to moderate hyperoxia

CM Bartman, L Nesbitt, KK Lee, L Khalfaoui… - Physiological …, 2024 - Wiley Online Library
Supplemental O2 (hyperoxia) is a critical intervention for premature infants (< 34 weeks) but
consequently is associated with development of bronchial airway hyperreactivity (AHR) and …

Exogenous hydrogen sulfide attenuates hyperoxia effects on neonatal mouse airways

CM Bartman, M Schiliro, L Nesbitt… - … of Physiology-Lung …, 2024 - journals.physiology.org
Supplemental O2 remains a necessary intervention for many premature infants (< 34 wk
gestation). Even moderate hyperoxia (< 60% O2) poses a risk for subsequent airway …

Endothelial Cpt1a Inhibits Neonatal Hyperoxia‐Induced Pulmonary Vascular Remodeling by Repressing Endothelial‐Mesenchymal Transition

X Li, K Hegarty, F Lin, JL Chang, A Abdalla… - Advanced …, 2025 - Wiley Online Library
Pulmonary hypertension (PH) increases the mortality of preterm infants with
bronchopulmonary dysplasia (BPD). There are no curative therapies for this disease. Lung …

Impact of different tissue dissociation protocols on endothelial cell recovery from developing mouse lungs

F Palumbo, M Gunjak, PJ Lee, S Günther… - Cytometry Part …, 2024 - Wiley Online Library
Flow cytometry and fluorescence‐activated cell sorting are widely used to study endothelial
cells, for which the generation of viable single‐cell suspensions is an essential first step …