[HTML][HTML] Exploring a potential palonosetron allosteric binding site in the 5-HT3 receptor
M Del Cadia, F De Rienzo, DA Weston… - Bioorganic & medicinal …, 2013 - Elsevier
Palonosetron (Aloxi) is a potent second generation 5-HT 3 receptor antagonist whose
mechanism of action is not yet fully understood. Palonosetron acts at the 5-HT 3 receptor …
mechanism of action is not yet fully understood. Palonosetron acts at the 5-HT 3 receptor …
Dendrimeric tetravalent ligands for the serotonin-gated ion channel
Multivalency is widely used in nature in specific recognition processes. This paper describes
an approach to multivalency in the pentameric 5-HT3 receptor, a ligand-gated ion channel …
an approach to multivalency in the pentameric 5-HT3 receptor, a ligand-gated ion channel …
Insight into the intermolecular recognition mechanism involved in complement component 4 activation through serine protease-trypsin
Serine protease cleaved-complement component 4 (C4) at sessile loop, which is significant
for completion of lectin and classical complement pathways at the time of infections. The co …
for completion of lectin and classical complement pathways at the time of infections. The co …
[HTML][HTML] Characterizing the hot spots involved in RON-MSPβ complex formation using in silico alanine scanning mutagenesis and molecular dynamics simulation
O Zarei, M Hamzeh-Mivehroud… - Advanced …, 2017 - ncbi.nlm.nih.gov
Purpose: Implication of protein-protein interactions (PPIs) in development of many diseases
such as cancer makes them attractive for therapeutic intervention and rational drug design …
such as cancer makes them attractive for therapeutic intervention and rational drug design …
[PDF][PDF] Activation and inhibition study of human complement component 4–a structural perspective
VK Sinha - 2017 - dspace.pondiuni.edu.in
PERSPECTIVE” submitted to the Pondicherry University for the award of degree of DOCTOR
OF PHILOSOPHY is a bonafide record of research work done by the candidate, Mr. Vikrant …
OF PHILOSOPHY is a bonafide record of research work done by the candidate, Mr. Vikrant …
Approaching the 5-HT3 receptor heterogeneity by computational studies of the transmembrane and intracellular domains
M Del Cadia, F De Rienzo, MC Menziani - Journal of computer-aided …, 2013 - Springer
hydroxytryptamine type-3 receptor (5-HT 3), an important target of many neuroactive drugs,
is a cation selective transmembrane pentamer whose functional stoichiometries and subunit …
is a cation selective transmembrane pentamer whose functional stoichiometries and subunit …