AJ Metrano, AJ Chinn, CR Shugrue, EA Stone… - Chemical …, 2020 - ACS Publications
Low molecular weight synthetic peptides have been demonstrated to be effective catalysts for an increasingly wide array of asymmetric transformations. In many cases, these peptide …
S Krautwald, EM Carreira - Journal of the American Chemical …, 2017 - ACS Publications
This Perspective presents an overview of catalytic enantioselective transformations that allow convenient access to all stereoisomers of a given product with multiple stereogenic …
Recent developments in catalytic asymmetric aldol reactions have been summarized. Enantioselective aldol reactions are important methods to synthesize β-hydroxy carbonyl …
SD Roughley, AM Jordan - Journal of medicinal chemistry, 2011 - ACS Publications
Industrial medicinal chemistry departments the world over are charged with the rapid delivery of small molecule new chemical entities (NCEs) into the screening process to …
M Zhu, P Wang, Q Zhang, W Tang… - Angewandte Chemie …, 2022 - Wiley Online Library
As a fundamental and synthetically useful C− C bond formation reaction, the aldol reaction is one of the most versatile transformations in organic synthesis. However, despite extensive …
M Hönig, P Sondermann, NJ Turner… - Angewandte Chemie …, 2017 - Wiley Online Library
Recent developments of stereoselective biocatalytic and chemocatalytic methods are discussed. The review provides a guide to the use of biocatalytic methods in the area of …
Z Du, Z Shao - Chemical Society Reviews, 2013 - pubs.rsc.org
The combination of transition metal catalysis and organocatalysis as a new and exciting research area has attracted increasing attention as it can enable the development of …
γ-Butenolides, γ-butyrolactones, and derivatives, especially in enantiomerically pure form, constitute the structural core of numerous natural products which display an impressive …
Y Zhang, H Cai, X Gan, Z Jin - Science China Chemistry, 2024 - Springer
N-heterocyclic carbene-catalyzed enantioselective kinetic resolutions, dynamic kinetic resolutions, and desymmetrization reactions are systematically reviewed. The content is …