Loss of the blood-retinal barrier (BRB) integrity and subsequent damage to the
neurovascular unit in the retina are the underlying reasons for diabetic retinopathy (DR) …

Age-related macular degeneration (AMD) is a progressive, degenerative disease of the
human retina which in its most aggressive form is associated with the formation of macular …

Breast cancer exhibits the highest global incidence among all tumor types. Regardless of
the type of breast cancer, metastasis is a crucial cause of poor prognosis. Anoikis, a form of …

Non-neuronal cells are key to the complex cellular interplay that follows central nervous
system insult. To understand this interplay, we generated a single-cell atlas of immune, glial …

Macular edema is the pathological accumulation of fluid in the central retina. It is a
complication of many retinal diseases, including diabetic retinopathy, retinal vascular …

Diseases that result in retinal pigment epithelium (RPE) degeneration, such as age-related
macular degeneration (AMD), are among the leading causes of blindness worldwide …

The retina is one of the most metabolically active tissues in the body and utilizes glucose to
produce energy and intermediates required for daily renewal of photoreceptor cell outer …

Age-related macular degeneration (AMD) is a progressive disease of the retinal pigment
epithelium (RPE) and the retina leading to loss of central vision. Polymorphisms in genes …

Inherited retinal dystrophies (IRDs) are congenital retinal degenerative diseases that have
various inheritance patterns, including dominant, recessive, X-linked, and mitochondrial …

The retinal pigment epithelium (RPE) is a unique epithelium, with major roles which are
essential in the visual cycle and homeostasis of the outer retina. The RPE is a monolayer of …