Long-term neuroinflammation induced by influenza A virus infection and the impact on hippocampal neuron morphology and function
S Hosseini, E Wilk, K Michaelsen-Preusse… - Journal of …, 2018 - Soc Neuroscience
Acute influenza infection has been reported to be associated with neurological symptoms.
However, the long-term consequences of an infection with neurotropic and non-neurotropic …
However, the long-term consequences of an infection with neurotropic and non-neurotropic …
Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice
B Hatesuer, S Bertram, N Mehnert, MM Bahgat… - PLoS …, 2013 - journals.plos.org
Annual influenza epidemics and occasional pandemics pose a severe threat to human
health. Host cell factors required for viral spread but not for cellular survival are attractive …
health. Host cell factors required for viral spread but not for cellular survival are attractive …
[HTML][HTML] Deletion of Irf3 and Irf7 genes in mice results in altered interferon pathway activation and granulocyte-dominated inflammatory responses to influenza A …
B Hatesuer, HTT Hoang, P Riese, S Trittel… - Journal of innate …, 2017 - karger.com
The interferon (IFN) pathway plays an essential role in the innate immune response
following viral infections and subsequent shaping of adaptive immunity. Infections with …
following viral infections and subsequent shaping of adaptive immunity. Infections with …
Complex genetic architecture underlies regulation of influenza-A-virus-specific antibody responses in the collaborative cross
KE Noll, AC Whitmore, A West, MK McCarthy… - Cell reports, 2020 - cell.com
Host genetic factors play a fundamental role in regulating humoral immunity to viral infection,
including influenza A virus (IAV). Here, we utilize the Collaborative Cross (CC), a mouse …
including influenza A virus (IAV). Here, we utilize the Collaborative Cross (CC), a mouse …
Influenza vaccine is able to prevent neuroinflammation triggered by H7N7 IAV infection
L Demuth, M Ohm, K Michaelsen-Preusse… - Frontiers in …, 2023 - frontiersin.org
Influenza A virus (IAV) subtypes are a major cause of illness and mortality worldwide and
pose a threat to human health. Although IAV infection is considered a self-limiting respiratory …
pose a threat to human health. Although IAV infection is considered a self-limiting respiratory …
Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background
DL Shin, B Hatesuer, S Bergmann, T Nedelko… - Journal of …, 2015 - Am Soc Microbiol
Influenza virus infections represent a serious threat to human health. Both extrinsic and
intrinsic factors determine the severity of influenza. The MX dynamin-like GTPase 1 (Mx1) …
intrinsic factors determine the severity of influenza. The MX dynamin-like GTPase 1 (Mx1) …
The proteolytic activation of (H3N2) influenza A virus hemagglutinin is facilitated by different type II transmembrane serine proteases
N Kühn, S Bergmann, N Kösterke… - Journal of …, 2016 - Am Soc Microbiol
Cleavage of influenza virus hemagglutinin (HA) by host cell proteases is necessary for viral
activation and infectivity. In humans and mice, members of the type II transmembrane …
activation and infectivity. In humans and mice, members of the type II transmembrane …
The role of bacterial metabolism in human gut colonization
A Muñoz-Cazalla, I de Quinto, L Álvaro-Llorente… - International …, 2024 - Springer
Can we anticipate the emergence of the next pandemic antibiotic-resistant bacterial clone?
Addressing such an ambitious question relies on our ability to comprehensively understand …
Addressing such an ambitious question relies on our ability to comprehensively understand …
RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for …
Background The host response to influenza A infections is strongly influenced by host
genetic factors. Animal models of genetically diverse mouse strains are well suited to identify …
genetic factors. Animal models of genetically diverse mouse strains are well suited to identify …
Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles
MD Hein, P Arora, P Marichal-Gallardo, M Winkler… - BMC biology, 2021 - Springer
Background Infections with influenza A virus (IAV) cause high morbidity and mortality in
humans. Additional to vaccination, antiviral drugs are a treatment option. Besides FDA …
humans. Additional to vaccination, antiviral drugs are a treatment option. Besides FDA …