S Brouwers, I Sudano, Y Kokubo, EM Sulaica - The Lancet, 2021 - thelancet.com
Arterial hypertension is the most important contributor to the global burden of disease; however, disease control remains poor. Although the diagnosis of hypertension is still based …
Dr Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s advocating that hypertension is the result of many factors that interact to raise blood pressure and cause end …
Recent research on the gut microbiome has revealed the influence of gut microbiota (GM) on ischemic stroke pathogenesis and treatment outcomes. Alterations in the diversity …
GR Drummond, A Vinh, TJ Guzik… - Nature Reviews …, 2019 - nature.com
Hypertension affects 30% of adults and is the leading risk factor for heart attack and stroke. Traditionally, hypertension has been regarded as a disorder of two systems that are involved …
DH Ellison, P Welling - New England Journal of Medicine, 2021 - Mass Medical Soc
Salt Handling and Blood Pressure Salt intake is associated with blood pressure, but the relationship is complex. This review highlights the interplay among renal salt transport, salt …
X Jia, W Xu, L Zhang, X Li, R Wang… - Frontiers in Cellular and …, 2021 - frontiersin.org
Hyperlipidemia, defined as the presence of excess fat or lipids in the blood, has been considered as a high-risk factor and key indicator of many metabolic diseases. The gut …
Q Zeng, D Li, Y He, Y Li, Z Yang, X Zhao, Y Liu… - Scientific reports, 2019 - nature.com
The gut microbiota (GM) is related to obesity and other metabolic diseases. To detect GM markers for obesity in patients with different metabolic abnormalities and investigate their …
S Jiang, Y Shui, Y Cui, C Tang, X Wang, X Qiu, W Hu… - Redox biology, 2021 - Elsevier
Gut microbiota produce Trimethylamine N-oxide (TMAO) by metabolizing dietary phosphatidylcholine, choline, l-carnitine and betaine. TMAO is implicated in the …
DM Kaye, WA Shihata, HA Jama, K Tsyganov… - Circulation, 2020 - Am Heart Assoc
Background: High blood pressure (BP) continues to be a major, poorly controlled but modifiable risk factor for cardiovascular death. Among key Western lifestyle factors, a diet …