Purification of recombinant proteins constitutes a significant part of the downstream
processing in biopharmaceutical industries. Major costs involved in the production of bio …

Nowadays, treatment with specific antivenins is considered the only cure for snakebites
accidents. However, access to antivenom obstructs the successful implementation of the …

Antisense peptide technology is a valuable tool for deriving new biologically active
molecules and performing peptide–receptor modulation. It is based on the fact that peptides …

In recent years, affinity fusion-tag systems have become a popular technique for the
purification of recombinant proteins from crude extracts. However, several drawbacks …

Heparin, a polysulfated polyanionic member of the glycosaminoglycan family, is known to
specifically bind to a number of functionally important proteins. Based on the available …

Heparin, a member of the glycosaminoglycan family, is known to interact with more than 400
different types of proteins. For the past few decades, significant progress has been made to …

Background In this study, we have demonstrated the design, screening and selection of
peptide ligands for the affinity capture of human growth hormone (hGH) from yeast cell …

The group of synthetic low-molecular peptides exhibiting profound analgesic activity was
developed by modifying the salmon calcitonin molecule fragment sCT16-21, which retains …

Peptide affinity tags have become efficient tools for the purification of recombinant proteins
from biological mixtures. The most commonly used ligands in this type of affinity …

Biomimetic ligands have emerged to overcome disadvantages inherent in biological
ligands. In particular, the Ugi reaction can generate scaffolds where molecular diversity can …