Pullulan: A novel molecule for biomedical applications

RS Singh, N Kaur, V Rana, JF Kennedy - Carbohydrate polymers, 2017 - Elsevier
Pullulan is an imperative natural polymer produced commercially by yeast like fungus
Aureobasidium pullulans. It is non-toxic, non-immunogenic, non-carcinogenic and non …

Anticancer and anti-inflammatory properties of chitin and chitosan oligosaccharides

K Azuma, T Osaki, S Minami, Y Okamoto - Journal of functional …, 2015 - mdpi.com
Previous reports indicate that N-acetyl-d-glucosamine oligomers (chitin oligosaccharide;
NACOS) and d-glucosamine oligomers (chitosan oligosaccharide; COS) have various …

Chitosan for gene delivery: Methods for improvement and applications

D Chuan, T Jin, R Fan, L Zhou, G Guo - Advances in colloid and interface …, 2019 - Elsevier
Gene therapy is a promising strategy for treating challenging diseases. The successful
delivery of genes is a critical step for gene therapy. However, concerns about …

Targeting endothelial permeability in the EPR effect

B Lahooti, RG Akwii, FT Zahra, MS Sajib… - Journal of Controlled …, 2023 - Elsevier
The characteristics of the primary tumor blood vessels and the tumor microenvironment drive
the enhanced permeability and retention (EPR) effect, which confers an advantage towards …

Polymeric nanoparticles-siRNA as an emerging nano-polyplexes against ovarian cancer

U Rehman, N Parveen, A Sheikh… - Colloids and Surfaces B …, 2022 - Elsevier
Ovarian cancer (OC) is considered fifth-deadliest cancer globally responsible for high
mortality in women. As the conventional therapeutic and diagnostic approaches are …

Novel delivery approaches for cancer therapeutics

AK Mitra, V Agrahari, A Mandal, K Cholkar… - Journal of controlled …, 2015 - Elsevier
Currently, a majority of cancer treatment strategies are based on the removal of tumor mass
mainly by surgery. Chemical and physical treatments such as chemo-and radiotherapies …

Chitosan as a machine for biomolecule delivery: A review

Z Mohammadi, M Eini, A Rastegari, MR Tehrani - Carbohydrate Polymers, 2021 - Elsevier
The major role of biomolecules in treatment of different diseases has been proven by
several studies. However, the main drawback in successful treatment by these molecules is …

Chitosan-based nanoparticles for nucleic acid delivery: technological aspects, applications, and future perspectives

M Karayianni, T Sentoukas, A Skandalis, N Pippa… - Pharmaceutics, 2023 - mdpi.com
Chitosan is a naturally occurring polymer derived from the deacetylation of chitin, which is
an abundant carbohydrate found mainly in the shells of various marine and terrestrial …

Current developments in nanotechnology for improved cancer treatment, focusing on tumor hypoxia

C Dai Phung, TH Tran, HT Nguyen, JH Jeong… - Journal of Controlled …, 2020 - Elsevier
Hypoxia is a common feature of the tumor microenvironment, which is characterized by
tissue oxygen deficiency due to an aggressive proliferation of cancer cells. Hypoxia …

Recent advancement of molecular structure and biomaterial function of chitosan from marine organisms for pharmaceutical and nutraceutical application

B Li, J Elango, W Wu - Applied Sciences, 2020 - mdpi.com
Chitosan is an innate cationic biological polysaccharide polymer, naturally obtained from
chitin deacetylation, that possesses broad-spectrum properties such as antibacterial …