Immune-checkpoint inhibitor use in patients with cancer and pre-existing autoimmune diseases

A Tison, S Garaud, L Chiche, D Cornec… - Nature Reviews …, 2022 - nature.com
Immune-checkpoint inhibitors (ICIs) have dramatically changed the management of
advanced cancers. Designed to enhance the antitumour immune response, they can also …

Nanozyme-based electrochemical biosensors for disease biomarker detection

RG Mahmudunnabi, FZ Farhana, N Kashaninejad… - Analyst, 2020 - pubs.rsc.org
In recent years, a new group of nanomaterials named nanozymes that exhibit enzyme-
mimicking catalytic activity has emerged as a promising alternative to natural enzymes …

Au-loaded superparamagnetic mesoporous bimetallic CoFeB nanovehicles for sensitive autoantibody detection

Y Kang, MK Masud, Y Guo, Y Zhao, ZS Nishat, J Zhao… - ACS …, 2023 - ACS Publications
Construction of a well-defined mesoporous nanostructure is crucial for applying nonnoble
metals in catalysis and biomedicine owing to their highly exposed active sites and …

Recent achievements and challenges on nanomaterial based electrochemical biosensors for the detection of colon and lung cancer biomarkers

SI Kaya, G Ozcelikay, F Mollarasouli… - Sensors and Actuators B …, 2022 - Elsevier
Cancer is still one of the leading diseases and causes of death in the world. More than 200
types of cancers are currently known. Early diagnosis still is an important integral part of …

systematic review on electrochemical biosensing of breast cancer miRNAs to develop alternative DCIS diagnostic tool

S Sornambikai, H Amir, G Bhuvaneshwari… - ECS Sensors …, 2022 - iopscience.iop.org
Till date, no systematic review is conducted on electrochemical biosensing of multiplexed
breast cancer miRNAs to identify their suitability as an alternative diagnostic tool for ductal …

Advanced liquid biopsy technologies for circulating biomarker detection

N Soda, BHA Rehm, P Sonar, NT Nguyen… - Journal of Materials …, 2019 - pubs.rsc.org
Liquid biopsy is a new diagnostic concept that provides important information for monitoring
and identifying tumor genomes in body fluid samples. Detection of tumor origin …

Lanthanide upconversion and downshifting luminescence for biomolecules detection

G Sun, Y Xie, L Sun, H Zhang - Nanoscale Horizons, 2021 - pubs.rsc.org
Biomolecules play critical roles in biological activities and are closely related to various
disease conditions. The reliable, selective and sensitive detection of biomolecules holds …

[HTML][HTML] Serum autoantibodyome reveals that healthy individuals share common autoantibodies

M Shome, Y Chung, R Chavan, JG Park, J Qiu… - Cell reports, 2022 - cell.com
Autoantibodies are a hallmark of both autoimmune disease and cancer, but they also occur
in healthy individuals. Here, we perform a meta-analysis of nine datasets and focus on the …

Blood protein biomarkers in lung cancer

H Huang, Y Yang, Y Zhu, H Chen, Y Yang, L Zhang… - Cancer Letters, 2022 - Elsevier
Lung cancer has consistently ranked first as the cause of cancer-associated mortality. The 5-
year survival rate has risen slowly, and the main obstacle to improving the prognosis of …

Review of technological challenges in personalised medicine and early diagnosis of neurodegenerative disorders

C Domínguez-Fernández, J Egiguren-Ortiz… - International Journal of …, 2023 - mdpi.com
Neurodegenerative disorders are characterised by progressive neuron loss in specific brain
areas. The most common are Alzheimer's disease and Parkinson's disease; in both cases …