A variety of targeted anticancer agents have been successfully introduced into clinical
practice, largely reflecting their ability to inhibit specific molecular alterations that are …

Surgery is an important treatment modality for the majority of solid organ cancers.
Unfortunately, cancer recurrence following surgery of curative intent is common, and …

Purpose Cancer-related mortality, a leading cause of death worldwide, is often the result of
metastatic disease recurrence. Anesthetic techniques have varying effects on innate and …

The purpose of this white paper is to provide a succinct summary of the different
experimental approaches that have been used in preclinical post-operative cognitive …

Rationale: Sepsis is characterized by a dysregulated immune response to infection.
Norepinephrine, the cornerstone vasopressor used in septic shock, may contribute to …

Background The association between type of anesthesia used and recurrence of cancer
remains controversial. This retrospective cohort study compared the influence of total IV …

Inhaled anesthetics have been in clinical use for over 150 years and are still commonly used
in daily practice. The initial view of inhaled anesthetics as indispensable for general …

BACKGROUND: Whether propofol elicits a survival benefit over volatile anesthetics during
cancer surgery remains inconclusive. The primary aim of this systematic review and meta …

Postoperative cognitive dysfunction (POCD) is a severe neurological complication after
anesthesia and surgery. However, there is still a lack of effective clinical pharmacotherapy …

The aging population is burgeoning globally and this trend presents great challenges to the
current healthcare system as the growing number of aged individuals receives procedures …