Cancer stem cells: advances in knowledge and implications for cancer therapy

X Chu, W Tian, J Ning, G Xiao, Y Zhou… - … and Targeted Therapy, 2024 - nature.com
Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

Cancer stem cells—origins and biomarkers: perspectives for targeted personalized therapies

L Walcher, AK Kistenmacher, H Suo, R Kitte… - Frontiers in …, 2020 - frontiersin.org
The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …

Cancer stem cells in colorectal cancer and the association with chemotherapy resistance

X Lei, Q He, Z Li, Q Zou, P Xu, H Yu, Y Ding, W Zhu - Medical Oncology, 2021 - Springer
The incidence and mortality of colorectal cancer (CRC) have always been among the
highest in the world, although the diagnosis and treatment are becoming more and more …

Reliability of CD44, CD24, and ALDH1A1 immunohistochemical staining: Pathologist assessment compared to quantitative image analysis

L Yaghjyan, YJ Heng, GM Baker, V Bret-Mounet… - Frontiers in …, 2022 - frontiersin.org
Background The data on the expression of stem cell markers CD44, CD24, and ALDH1A1 in
the breast tissue of cancer-free women is very limited and no previous studies have …

Cancer-associated stemness and epithelial-to-mesenchymal transition signatures related to breast invasive carcinoma prognostic

IM Groza, C Braicu, A Jurj, O Zanoaga, R Lajos… - Cancers, 2020 - mdpi.com
Simple Summary Breast cancer is one of the most common oncological diseases in women,
as its incidence is rapidly growing. In this study, we have investigated the mechanism of …

[HTML][HTML] Indentification of breast cancer subtypes sensitive to HCQ-induced autophagy inhibition

P Wang, Y Du, J Wang - Pathology-Research and Practice, 2019 - Elsevier
Background Breast cancer is the most frequent carcinoma in females, which could be
classified to 4 subtypes and the current treatment is still far from satisfactory. In this study, we …

Associations of stem cell markers CD44, CD24 and ALDH1A1 with mammographic breast density in women with benign breast biopsies

L Yaghjyan, YJ Heng, GM Baker, D Murthy… - British Journal of …, 2024 - nature.com
Background We examined associations of CD44, CD24 and ALDH1A1 breast stem cell
markers with mammographic breast density (MBD), a well-established breast cancer (BCa) …

[HTML][HTML] Associations of stem cell markers in benign breast tissue with subsequent breast cancer risk

L Yaghjyan, YJ Heng, GM Baker, D Murthy… - American Journal of …, 2023 - ncbi.nlm.nih.gov
We examined associations of stem cell markers CD44, CD24, and ALDH1A1 in benign
breast biopsy samples with subsequent breast cancer (BCa) risk and explored if these …

[HTML][HTML] Associations of reproductive breast cancer risk factors with expression of stem cell markers in benign breast tissue

L Yaghjyan, YJ Heng, GM Baker… - Frontiers in …, 2024 - frontiersin.org
Background We investigated the associations of reproductive factors known to influence
breast cancer risk with the expression of breast stem cell markers CD44, CD24, and …

[HTML][HTML] Reproductive factors and expression of stem cell markers in women with incident benign breast disease

T Wang, YJ Heng, BR Sardella… - American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Reproductive factors are well-established risk factors for breast cancer. The prevailing
hypothesis suggested that stem cell changes may be the key underlying mechanisms, but …