Cancer cachexia: definition, staging, and emerging treatments

J Ni, L Zhang - Cancer management and research, 2020 - Taylor & Francis
Cachexia is a multifactorial disease characterized by weight loss via skeletal muscle and
adipose tissue loss, an imbalance in metabolic regulation, and reduced food intake. It is …

Clinical impact of nutrition and inflammation assessment tools in gastric cancer treatment

T Aoyama, K Hara, K Kazama… - Anticancer Research, 2022 - ar.iiarjournals.org
The standard treatment for gastric cancer is surgical resection and perioperative adjuvant
treatment. Multidisciplinary treatment for gastric cancer leads to nutritional and inflammatory …

The impact of the age-adjusted Charlson comorbidity index as a prognostic factor for endoscopic papillectomy in ampullary tumors

Y Takada, H Kawashima, E Ohno, T Ishikawa… - Journal of …, 2022 - Springer
Background The prognostic nutritional index (PNI) and Charlson comorbidity index (CCI)
have been useful for predicting the prognosis based on nutritional condition and …

Association between systemic inflammation and malnutrition with survival in patients with cancer sarcopenia—a prospective multicenter study

GT Ruan, YZ Ge, HL Xie, CL Hu, Q Zhang… - Frontiers in …, 2022 - frontiersin.org
Objective Systemic inflammation and malnutrition are correlated with cancer sarcopenia and
have deleterious effects on oncological outcomes. However, the combined effect of …

Prognostic significance of the skeletal muscle index and systemic inflammatory index in patients with lymph node-positive breast cancer after radical mastectomy

R Tang, JP Deng, L Zhang, WW Zhang, JY Sun, F Chi… - BMC cancer, 2022 - Springer
Background The role of skeletal muscle index (SMI) and systemic inflammation index (SII)
for patients with lymph node-positive breast cancer remain controversial. This retrospective …

Deep learning–based assessment of CT markers of sarcopenia and myosteatosis for outcome assessment in patients with advanced pancreatic cancer after high …

S Nowak, C Kloth, M Theis, M Marinova… - European …, 2024 - Springer
Objectives To evaluate the prognostic value of CT-based markers of sarcopenia and
myosteatosis in comparison to the Eastern Cooperative Oncology Group (ECOG) score for …

Optimization of older adults by a geriatric assessment–guided multidisciplinary clinic before CAR T-cell therapy

SJ Yates, JF Cursio, A Artz, K Kordas… - Blood …, 2024 - ashpublications.org
The optimal means of assessing candidacy of older adults (≥ 65 years) for chimeric antigen
receptor T-cell (CAR-T) therapy are unknown. We explored the role of a geriatric …

Immune landscape and prognostic gene signatures in gastric cancer: implications for cachexia and clinical outcomes

X Sui, G Wu - Frontiers in Immunology, 2023 - frontiersin.org
Cachexia, a debilitating condition that worsens patient outcomes, often accompanies gastric
cancer, a malignancy that is prevalent worldwide. The extensive research explored the …

Prediction study of prognostic nutrition index on the quality of life of patients with cervical cancer undergoing radiotherapy and chemotherapy

Y Chen, B Huang, J Zheng, F He - PeerJ, 2023 - peerj.com
Objective To assess the prognostic nutritional index (PNI) and quality of life (QOL) of patients
with cervical cancer (CC) who underwent radiotherapy and chemotherapy and to reveal the …

Association of Systemic Inflammation and Overall Survival in Elderly Patients with Cancer Cachexia–Results from a Multicenter Study

GT Ruan, M Yang, XW Zhang, MM Song… - Journal of …, 2021 - Taylor & Francis
Background Systemic inflammation and cachexia are associated with adverse clinical
outcomes in elderly patients with cancer. The survival outcomes of elderly patients with …