Reactive oxygen species in cell signaling

VJ Thannickal, BL Fanburg - American Journal of …, 2000 - journals.physiology.org
Reactive oxygen species (ROS) are generated as by-products of cellular metabolism,
primarily in the mitochondria. When cellular production of ROS overwhelms its antioxidant …

Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells

J Boonstra, JA Post - Gene, 2004 - Elsevier
Cell cycle progression is regulated by a wide variety of external factors, amongst them are
growth factors and extracellular matrix factors. During the last decades evidence has been …

Evolution of catalases from bacteria to humans

M Zamocky, PG Furtmüller, C Obinger - Antioxidants & redox …, 2008 - liebertpub.com
Excessive hydrogen peroxide is harmful for almost all cell components, so its rapid and
efficient removal is of essential importance for aerobically living organisms. Conversely …

Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis

CS Sander, H Chang, F Hamm… - International journal …, 2004 - Wiley Online Library
Melanoma and nonmelanoma skin cancers are among the most prevalent cancers in the
human population. Solar ultraviolet radiation is considered a major etiological factor but the …

Mitochondrial redox control of matrix metalloproteinases

KK Nelson, JA Melendez - Free Radical Biology and Medicine, 2004 - Elsevier
Reactive oxygen species (ROS) are constantly generated in aerobic organisms during
normal metabolism and in response to both internal and external stimuli. Imbalances in the …

The pathogenesis of pterygium: current concepts and their therapeutic implications

J Chui, N Di Girolamo, D Wakefield, MT Coroneo - The ocular surface, 2008 - Elsevier
Pterygium is a disease of the ocular surface that is associated with chronic UV exposure and
is characterized by proliferation, inflammatory infiltrates, fibrosis, angiogenesis and …

Artifacts in cell culture: rapid generation of hydrogen peroxide on addition of (−)-epigallocatechin,(−)-epigallocatechin gallate,(+)-catechin, and quercetin to commonly …

LH Long, MV Clement, B Halliwell - Biochemical and Biophysical Research …, 2000 - Elsevier
There is considerable current interest in the possible beneficial health effects of quercetin,
catechins, epigallocatechins, epigallocatechin gallates, and related phenolic compounds …

Role of hydrogen peroxide and oxidative stress in healing responses

M Rojkind, JA Dominguez-Rosales, N Nieto… - Cellular and Molecular …, 2002 - Springer
Oxidative stress is a host defense mechanism whose involvement in maintaining
homeostasis and/or inducing disease has been widely investigated over the past decade …

Photooxidation of Amplex Red to resorufin: implications of exposing the Amplex Red assay to light

B Zhao, FA Summers, RP Mason - Free radical biology and medicine, 2012 - Elsevier
The Amplex Red assay, a fluorescent assay for the detection of H2O2, relies on the reaction
of H2O2 and colorless, nonfluorescent Amplex Red with a 1: 1 stoichiometry to form colored …

Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity

K Dittmann, C Mayer, HP Rodemann - Radiotherapy and Oncology, 2005 - Elsevier
BACKGROUND AND PURPOSE: Inhibition of EGFR-function can induce radiosensitization
in tumor cells. Purpose of our investigation was to identify the possible molecular …