Adolescence as a sensitive period of brain development

D Fuhrmann, LJ Knoll, SJ Blakemore - Trends in cognitive sciences, 2015 - cell.com
Most research on sensitive periods has focussed on early sensory, motor, and language
development, but it has recently been suggested that adolescence might represent a second …

Mechanisms contributing to prefrontal cortex maturation during adolescence

A Caballero, R Granberg, KY Tseng - Neuroscience & Biobehavioral …, 2016 - Elsevier
Adolescence is defined as a transitional period between childhood and adulthood
characterized by changes in social interaction and acquisition of mature cognitive abilities …

Persistent cannabis users show neuropsychological decline from childhood to midlife

MH Meier, A Caspi, A Ambler… - Proceedings of the …, 2012 - National Acad Sciences
Recent reports show that fewer adolescents believe that regular cannabis use is harmful to
health. Concomitantly, adolescents are initiating cannabis use at younger ages, and more …

Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review

THM Moore, S Zammit, A Lingford-Hughes… - The Lancet, 2007 - thelancet.com
Background Whether cannabis can cause psychotic or affective symptoms that persist
beyond transient intoxication is unclear. We systematically reviewed the evidence pertaining …

Structural and functional imaging studies in chronic cannabis users: a systematic review of adolescent and adult findings

A Batalla, S Bhattacharyya, M Yuecel, P Fusar-Poli… - PloS one, 2013 - journals.plos.org
Background The growing concern about cannabis use, the most commonly used illicit drug
worldwide, has led to a significant increase in the number of human studies using …

Evidence for the risks and consequences of adolescent cannabis exposure

A Levine, K Clemenza, M Rynn, J Lieberman - Journal of the American …, 2017 - Elsevier
Objective This review of the scientific literature examines the potential adult sequelae of
exposure to cannabis and related synthetic cannabinoids in adolescence. We examine the …

Synaptic functions of endocannabinoid signaling in health and disease

A Araque, PE Castillo, OJ Manzoni, R Tonini - Neuropharmacology, 2017 - Elsevier
Endocannabinoids (eCBs) are a family of lipid molecules that act as key regulators of
synaptic transmission and plasticity. They are synthetized “on demand” following …

Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal …

A Caspi, TE Moffitt, M Cannon, J McClay, R Murray… - Biological …, 2005 - Elsevier
BACKGROUND: Recent evidence documents that cannabis use by young people is a
modest statistical risk factor for psychotic symptoms in adulthood, such as hallucinations and …

Gene–environment interplay and psychopathology: Multiple varieties but real effects

M Rutter, TE Moffitt, A Caspi - Journal of child Psychology and …, 2006 - Wiley Online Library
Gene–environment interplay is a general term that covers several divergent concepts with
different meanings and different implications. In this review, we evaluate research evidence …

Adolescent drug exposure: A review of evidence for the development of persistent changes in brain function

H Salmanzadeh, SM Ahmadi-Soleimani… - Brain research …, 2020 - Elsevier
Over the past decade, many studies have indicated that adolescence is a critical period of
brain development and maturation. The refinement and maturation of the central nervous …