The advent of high-throughput single-cell transcriptomic analysis of microglia has revealed
different phenotypes that are inherently associated with disease conditions. A common …

Alzheimer's disease (AD) is the most common cause of dementia and is characterized by the
deposition of extracellular aggregates of amyloid-β (Aβ), the formation of intraneuronal tau …

Parkinson's Disease (PD) is a neurodegenerative and progressive disorder characterised by
intracytoplasmic inclusions called Lewy bodies (LB) and degeneration of dopaminergic …

There is a plethora of evidence to suggest that Galectin-3 plays an important role in normal
functions of mammalian cells, as well as in different pathogenic conditions. This review …

Galectins are soluble β‐galactoside‐binding proteins found in all multicellular organisms.
Galectins may act as danger‐associated molecular patterns in innate immunity and/or as …

Galectins are β-galactoside-binding lectins consisting of 15 members in mammals. Galectin-
1,-3,-4,-8, and-9 are predominantly expressed in the central nervous system (CNS) and …

Cognitive impairment may be a consequence of the normal aging process, but it may also
be the hallmark of various neurodegenerative and psychiatric diseases. Early identification …

Neurodegeneration is a pathological condition that is associated with the loss of neuronal
function and structure. In neurodegenerative diseases, mounting evidence indicates that …

Parkinson's disease (PD) is a neurodegenerative disease. Repetitive transcranial magnetic
stimulation (rTMS) is a therapeutic tool in PD. High-throughput sequencing was performed to …

Microglial activation is one of the common hallmarks shared by various central nervous
system (CNS) diseases. Based on surrounding circumstances, activated microglia play …