The X-linked bleeding disorder hemophilia is caused by mutations in coagulation factor VIII
(hemophilia A) or factor IX (hemophilia B). Unless prophylactic treatment is provided …

Blood outgrowth endothelial cells (BOECs) are important tools when investigating diagnostic
and therapeutic approaches for vascular disease. In this protocol, mononuclear cells are …

Hemophilia is an inherited bleeding disorder caused by a deficiency of functional clotting
factors VIII or IX in the blood plasma. The drawbacks of the classical protein substitution …

In the majority of patients with acquired thrombotic thrombocytopenic purpura (TTP),
antibodies are directed toward the spacer domain of ADAMTS13. We have previously …

Vascular endothelial cells contain unique storage organelles, designated Weibel-Palade
bodies (WPBs), that deliver inflammatory and hemostatic mediators to the vascular lumen in …

Abstract Background The von Willebrand factor (VWF) is a multimeric plasma glycoprotein
essential for hemostasis, inflammation, and angiogenesis. The majority of VWF is …

Hemophilia A (HA) is a rare bleeding disorder caused by deficiency/dysfunction of the FVIII
protein. As current therapies based on frequent FVIII infusions are not a definitive cure, long …

Bibliographie Page 1 Bibliographie Agar, M./Reisinger, HS (2001): Using Trend Theory to
Explain Heroin Use Trends. In: Journal of Psychoactive Drugs 33 (3), 203–211. Agar, Nicholas …

Background Endothelial colony forming cells (ECFCs) derived from peripheral blood can be
used to analyze the pathophysiology of vascular diseases ex vivo. However, heterogeneity …

Coagulation factors are produced from hepatocytes, whereas production of coagulation
factor VIII (FVIII) from primary tissues and cell species is still controversial. Here, we tried to …