Context Urothelial carcinoma can exhibit a wide range of variant morphologies. Many
variants present diagnostic challenges and carry clinical implications that inform prognosis …

In the past 10 years evidence for the clinical relevance of variant histology in urinary bladder
cancer has been increasing. This increase has resulted in new classifications of urothelial …

Context Variant histology of muscle-invasive (MIBC) and metastatic (mBC) bladder cancer
may define the cancer treatment modality and oncological outcomes. Objective To …

Objectives To evaluate variant histologies (VHs) for disease‐specific survival (DSS) in
patients with invasive urothelial bladder cancer (BCa) undergoing radical cystectomy (RC) …

Context Neoadjuvant chemotherapy (NAC) is recommended prior to radical cystectomy in
the setting of muscle-invasive bladder cancer. Despite a 5–10% survival benefit, some …

Background The use of adjuvant chemotherapy (AC) in pure urothelial carcinoma of the
bladder is established. Regarding variant histology, there is a gap in knowledge concerning …

Objectives To determine the clinical characteristics, treatment patterns, and outcomes of
patients with nonurothelial cell bladder cancer (NUBC) in the United States. Methods A total …

Objective To evaluate the incidence and survival outcomes of histological variants of upper
tract urothelial carcinoma (UTUC) treated with radical nephroureterectomy (RNU). Materials …

Clinically, the surgical treatment of bladder cancer often faces the problem of tumor
recurrence, and the surgical treatment combined with postoperative chemotherapy to inhibit …

Background: The most common bladder cancer (BC) histotype is pure urothelial carcinoma
(UC), which may undergo divergent differentiation in some cases. Variant histology (VH) …