Microscopic biological processes have extraordinary complexity and variety at the sub-
cellular, intra-cellular, and multi-cellular levels. In dealing with such complex phenomena …

The chemotactic network of Escherichia coli has been studied extensively both biophysically
and information theoretically. Nevertheless, connection between these two aspects is still …

Transitions in the qualitative behavior of chemical reaction dynamics with a decrease in
molecule number have attracted much attention. Here, a method based on a Markov …

Despite being governed by the principles of nonequilibrium transitions, gene expression
dynamics underlying cell fate decision is poorly understood. In particular, the effect of …

Noise-induced symmetry breaking has barely been unveiled on the ecological grounds,
though its occurrence may elucidate mechanisms responsible for maintaining biodiversity …

In this study, we study noise-induced bistability in a simple bivariate mutual inhibition system
with slow fluctuating responses to external signals. We give a general condition that the …

The Togashi Kaneko model (TK model), introduced by Togashi and Kaneko in 2001, is a
simple stochastic reaction network that displays discreteness-induced transitions between …

The number of molecules involved in a cell or subcellular structure is sometimes rather
small. In this situation, ordinary macroscopic-level fluctuations can be overwhelmed by non …

Stochasticity or noise is omnipresent in ecosystems that mediates community dynamics. The
beneficial role of stochasticity in enhancing species coexistence and, hence, in promoting …

Induction of a specific transcriptional program by external signaling inputs is a crucial aspect
of intracellular network functioning. The theoretical concept of coexisting attractors …