Anticoagulants: a short history, their mechanism of action, pharmacology, and indications

M Heestermans, G Poenou, H Hamzeh-Cognasse… - Cells, 2022 - mdpi.com
Anticoagulant drugs antagonize coagulation and are used to prevent or cure (recurrent)
venous thromboembolism (VTE). Drugs to prevent clotting have been used for more than a …

[HTML][HTML] Outcomes of venous thromboembolism care: future directions

CMM de Jong, RP Rosovsky, FA Klok - Journal of Thrombosis and …, 2023 - Elsevier
The complete picture of the outcomes of venous thromboembolism (VTE) care consists of
conventional binary clinical outcomes (death, recurrent VTE, and bleeding), patient-centered …

Chronic thromboembolic pulmonary hypertension and impairment after pulmonary embolism: the FOCUS study

L Valerio, AC Mavromanoli, S Barco… - European Heart …, 2022 - academic.oup.com
Aims To systematically assess late outcomes of acute pulmonary embolism (PE) and to
investigate the clinical implications of post-PE impairment (PPEI) fulfilling prospectively …

Incidence and impact of anticoagulation-associated abnormal menstrual bleeding in women after venous thromboembolism

CMM de Jong, M Blondon, C Ay… - Blood, The Journal …, 2022 - ashpublications.org
Preliminary data and clinical experience have suggested an increased risk of abnormal
uterine bleeding (AUB) in women of reproductive age treated with anticoagulants, but solid …

Cardiopulmonary exercise testing during follow-up after acute pulmonary embolism

IT Farmakis, L Valerio, S Barco… - European …, 2023 - Eur Respiratory Soc
Background Cardiopulmonary exercise testing (CPET) may provide prognostically valuable
information during follow-up after pulmonary embolism (PE). Our objective was to …

[HTML][HTML] Management of bleeding risk in patients who receive anticoagulant therapy for venous thromboembolism: Communication from the ISTH SSC Subcommittee …

PL den Exter, SC Woller, H Robert‐Ebadi… - Journal of Thrombosis …, 2022 - Elsevier
Patients with acute venous thromboembolism (VTE) require anticoagulant therapy to prevent
recurrent VTE and death, which exposes them to an inherent increased risk of bleeding …

Cost‐of‐Illness Analysis of Long‐Term Health Care Resource Use and Disease Burden in Patients With Pulmonary Embolism: Insights From the PREFER in VTE …

IT Farmakis, S Barco, AC Mavromanoli… - Journal of the …, 2022 - Am Heart Assoc
Background As mortality from pulmonary embolism (PE) decreases, the personal and
societal costs among survivors are receiving increasing attention. Detailing this burden …

Systematic pulmonary embolism follow-up increases diagnostic rates of chronic thromboembolic pulmonary hypertension and identifies less severe disease: results …

C Durrington, JA Hurdman, CA Elliot… - European …, 2024 - Eur Respiratory Soc
Background Diagnostic rates and risk factors for the subsequent development of chronic
thromboembolic pulmonary hypertension (CTEPH) following pulmonary embolism (PE) are …

The Post–Venous Thromboembolism Functional Status Scale: From Call to Action to Application in Research, Extension to COVID-19 Patients, and Its Use in Clinical …

CMM de Jong, GJAM Boon, YNJ Le… - … in Thrombosis and …, 2023 - thieme-connect.com
A broad spectrum of long-term sequelae may be present in venous thromboembolism (VTE)
survivors, affecting their quality of life and functioning. To monitor recovery and improve the …

Post-pulmonary embolism syndrome and functional outcomes after acute pulmonary embolism

D Luijten, CMM de Jong, MK Ninaber… - … in Thrombosis and …, 2022 - thieme-connect.com
Survivors of acute pulmonary embolism (PE) are at risk of developing persistent, sometimes
disabling symptoms of dyspnea and/or functional limitations despite adequate anticoagulant …