The pneumococcus is the classic Gram-positive extracellular pathogen. The medical burden
of diseases it causes is amongst the greatest in the world. Intense study for more than 100 …

Acinetobacter baumannii has emerged as a medically important pathogen because of the
increasing number of infections produced by this organism over the preceding three …

Streptococcus pneumoniae is a Gram-positive bacterial pathogen that colonizes the
mucosal surfaces of the host nasopharynx and upper airway. Through a combination of …

Streptococcus pneumoniae is a major pathogen of humans, causing diseases such as
pneumonia and meningitis. The organism produces several virulence factors that are …

The overall goal for this review is to summarize the current body of knowledge about the
structure and function of major known antigens of Streptococcus pneumoniae, a major gram …

Pneumolysin (PLY) is a key Streptococcus pneumoniae virulence factor and potential
candidate for inclusion in pneumococcal subunit vaccines. Dendritic cells (DC) play a key …

Streptococcus pneumoniae (the pneumoccus) is the leading cause of otitis media,
community-acquired pneumonia, and bacterial meningitis. The success of the …

The development of bacterial disease has been likened to a'molecular arms race', in which
the host tries to eliminate the bacteria, while the bacteria try to survive in the host. Although …

The choline binding proteins (CBPs) are a family of surface proteins noncovalently bound to
the phosphorylcholine moiety of the cell wall of Streptococcus pneumoniae by a conserved …

Pneumococcus is the most common and aggressive cause of bacterial meningitis and
induces a novel apoptosis-inducing factor–dependent (AIF–dependent) form of brain cell …