Ecology, evolution and spillover of coronaviruses from bats

M Ruiz-Aravena, C McKee, A Gamble, T Lunn… - Nature Reviews …, 2022 - nature.com
In the past two decades, three coronaviruses with ancestral origins in bats have emerged
and caused widespread outbreaks in humans, including severe acute respiratory syndrome …

[PDF][PDF] Novel coronavirus COVID-19: an overview for emergency clinicians

AL Giwa, A Desai - Emerg Med Pract, 2020 - ebmedicine.net
Coronaviruses earn their name from the characteristic crown-like viral particles (virions) that
dot their surface. This family of viruses infects a wide range of vertebrates, most notably …

Novel canine coronavirus isolated from a hospitalized patient with pneumonia in East Malaysia

AN Vlasova, A Diaz, D Damtie, L Xiu… - Clinical Infectious …, 2022 - academic.oup.com
Background During the validation of a highly sensitive panspecies coronavirus (CoV)
seminested reverse-transcription polymerase chain reaction (RT-PCR) assay, we found …

[HTML][HTML] The origin of COVID-19 and why it matters

DM Morens, JG Breman, CH Calisher… - The American journal …, 2020 - ncbi.nlm.nih.gov
The COVID-19 pandemic is among the deadliest infectious diseases to have emerged in
recent history. As with all past pandemics, the specific mechanism of its emergence in …

Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen

OA MacLean, S Lytras, S Weaver, JB Singer… - PLoS …, 2021 - journals.plos.org
Virus host shifts are generally associated with novel adaptations to exploit the cells of the
new host species optimally. Surprisingly, Severe Acute Respiratory Syndrome Coronavirus …

The animal origin of SARS-CoV-2

S Lytras, W Xia, J Hughes, X Jiang, DL Robertson - Science, 2021 - science.org
Although first detected in December 2019, COVID-19 was inferred to be present in Hubei
province, China, for about a month before. Where did this new human disease come from …

[HTML][HTML] COVID-19—zoonosis or emerging infectious disease?

N Haider, P Rothman-Ostrow, AY Osman… - Frontiers in Public …, 2020 - frontiersin.org
The World Health Organization defines a zoonosis as any infection naturally transmissible
from vertebrate animals to humans. The pandemic of Coronavirus disease (COVID-19) …

Review of current COVID-19 diagnostics and opportunities for further development

Y Mardian, H Kosasih, M Karyana, A Neal… - Frontiers in …, 2021 - frontiersin.org
Diagnostic testing plays a critical role in addressing the coronavirus disease 2019 (COVID-
19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV …

Surveillance of SARS-CoV-2 at the Huanan seafood market

WJ Liu, P Liu, W Lei, Z Jia, X He, W Shi, Y Tan, S Zou… - Nature, 2024 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019, emerged in December 2019. Its origins remain uncertain. It has …

[PDF][PDF] Exploring the natural origins of SARS-CoV-2 in the light of recombination

S Lytras, J Hughes, D Martin… - Genome Biology and …, 2022 - academic.oup.com
The lack of an identifiable intermediate host species for the proximal animal ancestor of
SARS-CoV-2, and the large geographical distance between Wuhan and where the closest …