Technology of deep brain stimulation: current status and future directions

JK Krauss, N Lipsman, T Aziz, A Boutet… - Nature Reviews …, 2021 - nature.com
Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

Advances in closed-loop deep brain stimulation devices

M Parastarfeizabadi, AZ Kouzani - Journal of neuroengineering and …, 2017 - Springer
Background Millions of patients around the world are affected by neurological and
psychiatric disorders. Deep brain stimulation (DBS) is a device-based therapy that could …

First-in-human prediction of chronic pain state using intracranial neural biomarkers

P Shirvalkar, J Prosky, G Chin, P Ahmadipour… - Nature …, 2023 - nature.com
Chronic pain syndromes are often refractory to treatment and cause substantial suffering
and disability. Pain severity is often measured through subjective report, while objective …

Gilles de la Tourette syndrome

MM Robertson, V Eapen, HS Singer… - Nature reviews Disease …, 2017 - nature.com
Gilles de la Tourette syndrome (GTS) is a childhood-onset neurodevelopmental disorder
that is characterized by several motor and phonic tics. Tics usually develop before 10 years …

Revolution of Alzheimer precision neurology. Passageway of systems biology and neurophysiology

H Hampel, N Toschi, C Babiloni… - Journal of …, 2018 - content.iospress.com
The Precision Neurology development process implements systems theory with system
biology and neurophysiology in a parallel, bidirectional research path: a combined …

Integrating brain implants with local and distributed computing devices: a next generation epilepsy management system

V Kremen, BH Brinkmann, I Kim… - IEEE journal of …, 2018 - ieeexplore.ieee.org
Brain stimulation has emerged as an effective treatment for a wide range of neurological and
psychiatric diseases. Parkinson's disease, epilepsy, and essential tremor have FDA …

Proceedings of the eighth annual deep brain stimulation think tank: advances in optogenetics, ethical issues affecting DBS research, neuromodulatory approaches for …

V Vedam-Mai, K Deisseroth, J Giordano… - Frontiers in Human …, 2021 - frontiersin.org
We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to
address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters …

Machine learning for adaptive deep brain stimulation in Parkinson's disease: closing the loop

AM Oliveira, L Coelho, E Carvalho… - Journal of …, 2023 - Springer
Parkinson's disease (PD) is the second most common neurodegenerative disease bearing a
severe social and economic impact. So far, there is no known disease modifying therapy …

Deep brain stimulation for the treatment of disorders of consciousness and cognition in traumatic brain injury patients: a review

B Kundu, AA Brock, DJ Englot, CR Butson… - Neurosurgical …, 2018 - thejns.org
Traumatic brain injury (TBI) is a looming epidemic, growing most rapidly in the elderly
population. Some of the most devastating sequelae of TBI are related to depressed levels of …

Oscillatory activity in the cortico‐basal ganglia‐thalamic neural circuits in Parkinson's disease

A Singh - European Journal of Neuroscience, 2018 - Wiley Online Library
Dopamine is an important neurotransmitter that maintains the balance within the basal
ganglia between the direct pathway, which promotes movement, and the indirect pathway …