[HTML][HTML] Vitamins as regulators of calcium-containing kidney stones—new perspectives on the role of the gut microbiome

JA Chmiel, GA Stuivenberg, KF Al, PP Akouris… - Nature Reviews …, 2023 - nature.com
Calcium-based kidney stone disease is a highly prevalent and morbid condition, with an
often complicated and multifactorial aetiology. An abundance of research on the role of …

Determination of an interaction network between an extracellular bacterial pathogen and the human host

B Griesenauer, TM Tran, KR Fortney, DM Janowicz… - MBio, 2019 - Am Soc Microbiol
ABSTRACT A major gap in understanding infectious diseases is the lack of information
about molecular interaction networks between pathogens and the human host …

[HTML][HTML] Streptococcus pneumoniae: a Plethora of Temperate Bacteriophages With a Role in Host Genome Rearrangement

AJ Martín-Galiano, E García - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Bacteriophages (phages) are viruses that infect bacteria. They are the most abundant
biological entity on Earth (current estimates suggest there to be perhaps 1031 particles) and …

A PTS EII mutant library in Group A Streptococcus identifies a promiscuous man‐family PTS transporter influencing SLS‐mediated hemolysis

GS Sundar, E Islam, K Gera, Y Le Breton… - Molecular …, 2017 - Wiley Online Library
Summary The Group A Streptococcus (GAS, Streptococcus pyogenes) is a Gram‐positive
human pathogen that must adapt to unique host environments in order to survive. Links …

Sialic Acid-Mediated Gene Expression in Streptococcus pneumoniae and Role of NanR as a Transcriptional Activator of the nan Gene Cluster

M Afzal, S Shafeeq, H Ahmed… - Applied and …, 2015 - Am Soc Microbiol
In this study, we investigated the transcriptomic response of Streptococcus pneumoniae D39
to sialic acid (N-acetylneuraminic acid [Neu5Ac]). Transcriptome comparison of wild-type …

A fast and reliable pipeline for bacterial transcriptome analysis case study: serine-dependent gene regulation in Streptococcus pneumoniae

M Afzal, I Manzoor, OP Kuipers - JoVE (Journal of Visualized Experiments), 2015 - jove.com
Gene expression and its regulation are very important to understand the behavior of cells
under different conditions. Various techniques are used nowadays to study gene …

[HTML][HTML] Transcriptional profiling of UlaR-regulated genes in Streptococcus pneumoniae

S Shafeeq, M Afzal, B Henriques-Normark, OP Kuipers - Genomics Data, 2015 - Elsevier
The transcriptional regulator UlaR belongs to the family of PRD-containing transcriptional
regulators, which are mostly involved in the regulation of carbohydrate metabolism. The role …

Haemophilus ducreyi seeks alternative carbon sources and adapts to nutrient stress and anaerobiosis during experimental infection of human volunteers

D Gangaiah, X Zhang, B Baker, KR Fortney… - Infection and …, 2016 - Am Soc Microbiol
Haemophilus ducreyi causes the sexually transmitted disease chancroid in adults and
cutaneous ulcers in children. In humans, H. ducreyi resides in an abscess and must adapt to …

[HTML][HTML] Maltose-Dependent Transcriptional Regulation of the mal Regulon by MalR in Streptococcus pneumoniae

M Afzal, S Shafeeq, I Manzoor, OP Kuipers - PLoS One, 2015 - journals.plos.org
The maltose regulon (mal regulon) has previously been shown to consist of the mal gene
cluster (malMP, malXCD and malAR operons) in Streptococcus pneumoniae. In this study …

[HTML][HTML] Ascorbic acid-dependent gene expression in Streptococcus pneumoniae and the activator function of the transcriptional regulator UlaR2

M Afzal, S Shafeeq, OP Kuipers - Frontiers in Microbiology, 2015 - frontiersin.org
In this study, we have explored the impact of ascorbic acid on the transcriptome of
Streptococcus pneumoniae D39. The expression of several genes and operons, including …