Obesity and cardiovascular disease: revisiting an old relationship

C Koliaki, S Liatis, A Kokkinos - Metabolism, 2019 - Elsevier
A wealth of clinical and epidemiological evidence has linked obesity to a broad spectrum of
cardiovascular diseases (CVD) including coronary heart disease, heart failure …

[HTML][HTML] The relationship between obesity and hypertension: an updated comprehensive overview on vicious twins

M Leggio, M Lombardi, E Caldarone, P Severi… - Hypertension …, 2017 - nature.com
Obesity is a growing global health concern, with a rapid increase being observed in morbid
obesity. Obesity is associated with an increased cardiovascular risk and earlier onset of …

Taurine is involved in energy metabolism in muscles, adipose tissue, and the liver

C Wen, F Li, L Zhang, Y Duan, Q Guo… - Molecular nutrition & …, 2019 - Wiley Online Library
Energy metabolism is a basic and general process, by which the body acquires and uses
energy to maintain normal function, and taurine plays a vital role in energy metabolism …

Cardiac remodeling in obesity

ED Abel, SE Litwin, G Sweeney - Physiological reviews, 2008 - journals.physiology.org
The dramatic increase in the prevalence of obesity and its strong association with
cardiovascular disease have resulted in unprecedented interest in understanding the effects …

Cardiovascular actions of insulin

R Muniyappa, M Montagnani, KK Koh… - Endocrine …, 2007 - academic.oup.com
Insulin has important vascular actions to stimulate production of nitric oxide from
endothelium. This leads to capillary recruitment, vasodilation, increased blood flow, and …

Obesity and cardiovascular disease: friend or foe?

SH Kim, JP Després, KK Koh - European heart journal, 2016 - academic.oup.com
Obesity is currently one of the greatest public health issues worldwide. However, despite its
known deleterious effects on the cardiovascular system and its association with numerous …

[HTML][HTML] Relationship between adiponectin, obesity and insulin resistance

GA Balsan, JLC Vieira, AM Oliveira… - Revista da Associação …, 2015 - SciELO Brasil
Objectives: the conditions of obesity and overweight pose a major risk for a number of
comorbidities, including clinical syndromes resulting from atherosclerotic disease. Recent …

Metabolic mechanisms in heart failure

H Ashrafian, MP Frenneaux, LH Opie - Circulation, 2007 - Am Heart Assoc
Although neurohumoral antagonism has successfully reduced heart failure morbidity and
mortality, the residual disability and death rate remains unacceptably high. Though …

[HTML][HTML] Adiponectin: a manifold therapeutic target for metabolic syndrome, diabetes, and coronary disease?

EZ Fisman, A Tenenbaum - Cardiovascular diabetology, 2014 - Springer
Adiponectin is the most abundant peptide secreted by adipocytes, being a key component in
the interrelationship between adiposity, insulin resistance and inflammation. Central obesity …

On the run for hippocampal plasticity

HY Moon, H van Praag - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Accumulating research in rodents and humans indicates that exercise benefits brain function
and may prevent or delay onset of neurodegenerative conditions. In particular, exercise …