Toxoplasma gondii in South America: a differentiated pattern of spread, population structure and clinical manifestations

G de Lima Bessa, RW de Almeida Vitor… - Parasitology …, 2021 - Springer
Toxoplasma gondii is an obligate intracellular parasite belonging to the phylum
Apicomplexa. It has a worldwide distribution and can infect a wide variety of intermediate …

[图书][B] Toxoplasmosis of animals and humans

JP Dubey - 2016 - taylorfrancis.com
Found worldwide from Alaska to Australasia, Toxoplasma gondii knows no geographic
boundaries. The protozoan is the source of one of the most common parasitic infections in …

Ocular toxoplasmosis, an overview focusing on clinical aspects

S Fabiani, C Caroselli, M Menchini, G Gabbriellini… - Acta Tropica, 2022 - Elsevier
Toxoplasma gondii is a widespread protozoan parasite infecting approximately one third of
the world population. After proliferation of tachyzoites during the acute stage, the parasite …

Evaluation of the impact of the first evidence-based guidelines for congenital toxoplasmosis in Armenia (Quindío) Colombia: An observational retrospective analysis

M Mejia-Oquendo, E Marulanda-Ibarra… - The Lancet Regional …, 2021 - thelancet.com
Background Colombia implemented the world's first evidence-based guidelines for
congenital toxoplasmosis in 2013, no evaluation of its impact has been reported. Methods …

LFA-1/ICAM-1 promotes NK cell cytotoxicity associated with the pathogenesis of ocular toxoplasmosis in murine model

N Gao, C Wang, Y Yu, L Xie, Y Xing… - PLOS Neglected …, 2022 - journals.plos.org
Ocular toxoplasmosis (OT) is one of the most common causes of posterior uveitis. However,
the pathogenic mechanisms of OT have not been well elucidated. Here, we used C57BL/6 …

Serotyping, a challenging approach for Toxoplasma gondii typing

S Sousa, M Fernandes, JM Correia da Costa - Frontiers in Medicine, 2023 - frontiersin.org
Genotype analysis has revealed a high genetic diversity in strains of Toxoplasma gondii,
isolated from a wide range of intermediate hosts and different geographic origins. Diversity …

Genetic Variations in the Purinergic P2X7 Receptor Are Associated with the Immune Response to Ocular Toxoplasmosis in Colombia

CA Naranjo-Galvis, R McLeod, JE Gómez-Marín… - Microorganisms, 2023 - mdpi.com
Ocular toxoplasmosis (OT) is characterized by inflammation within the eye and is the most
recognized clinical manifestation of toxoplasmosis. The objective of this study was to identify …

Role of interleukin 1β and interleukin 10 variants on ocular toxoplasmosis in Brazilian individuals

WMR Araujo, CM Ayo, M Previato… - Frontiers in …, 2023 - frontiersin.org
Introduction Ocular toxoplasmosis (OT) is an intraocular inflammation caused by
Toxoplasma gondii infection that affects the retina and choroid, giving rise to posterior …

CD8+ T–cell exhaustion phenotype in human asymptomatic and ocular toxoplasmosis

LL García-López, M Vargas-Montes… - Ocular Immunology …, 2024 - Taylor & Francis
This work analyzed exhaustion markers in CD8+ T-cell subpopulations in 21 samples of
peripheral blood mononuclear cells (PBMCs) from individuals with ocular toxoplasmosis (n …

Human T-cell activation with Toxoplasma gondii antigens loaded in maltodextrin nanoparticles

L García-López, A Zamora-Vélez… - Life Science …, 2024 - life-science-alliance.org
Toxoplasmosis is the most prevalent parasitic zoonosis worldwide, causing ocular and
neurological diseases. No vaccine has been approved for human use. We evaluated the …