[HTML][HTML] ASCL1 regulates and cooperates with FOXA2 to drive terminal neuroendocrine phenotype in prostate cancer
S Nouruzi, T Namekawa, N Tabrizian, M Kobelev… - JCI …, 2024 - pmc.ncbi.nlm.nih.gov
Lineage plasticity mediates resistance to androgen receptor pathway inhibitors (ARPIs) and
progression from adenocarcinoma to neuroendocrine prostate cancer (NEPC), a highly …
progression from adenocarcinoma to neuroendocrine prostate cancer (NEPC), a highly …
Neuroendocrine transdifferentiation in human cancer: molecular mechanisms and therapeutic targets
J Jiang, D Han, J Wang, W Wen, R Zhang, W Qin - MedComm, 2024 - Wiley Online Library
Neuroendocrine transdifferentiation (NEtD), also commonly referred to as lineage plasticity,
emerges as an acquired resistance mechanism to molecular targeted therapies in multiple …
emerges as an acquired resistance mechanism to molecular targeted therapies in multiple …
Redox regulation of cancer stem cells: Biology and therapeutic implications
M Du, J Zhang, MS Wicha, M Luo - MedComm–Oncology, 2024 - Wiley Online Library
Cancer stem cells (CSCs) are a small group of tumor cells with the capacity to undergo self‐
renewal and differentiation. These cells not only initiate and maintain tumor growth, but also …
renewal and differentiation. These cells not only initiate and maintain tumor growth, but also …
Multiomics mapping and characterization of cellular senescence in aging human muscle uncovers novel senotherapeutics for sarcopenia
Cellular senescence is recognized as a hallmark of organismal aging but how it drives aging
particularly in human tissues is not fully understood, partly due to the complex …
particularly in human tissues is not fully understood, partly due to the complex …
Multiomics mapping and characterization of cellular senescence in aging human skeletal muscle uncovers a novel senotherapeutic for sarcopenia
Cellular senescence is recognized as a hallmark of organismal aging but how it drives aging
particularly in human tissues is not fully understood, partly due to the complex …
particularly in human tissues is not fully understood, partly due to the complex …