Highlights•Bacterial size and chemical composition are thought to be growth rate-
dependent.•The correlation between growth rate and size is affected by nutrient …

The DnaA protein has long been considered to play the key role in the initiation of
chromosome replication in modern bacteria. Many questions about this role, however …

Cell division in bacteria is driven by a cytoskeletal ring structure, the Z ring, composed of
polymers of the tubulin-like protein FtsZ. Z-ring formation must be tightly regulated to ensure …

In this work we analyzed protein-protein interactions (PPIs) formed by E. coli replication
proteins under three disparate bacterial growth conditions. The chosen conditions …

The initiation of Escherichia coli chromosomal DNA replication starts with the
oligomerization of the DnaA protein at repeat sequences within the origin (ori) region. The …

Highlights•Metabolism and cell cycle are interconnected at multiple levels in bacteria.•DNA
replication and cytokinesis are processes subject to metabolic regulation.•DNA replication …

While the model bacteria Escherichia coli and Bacillus subtilis harbor single chromosomes,
which is known as monoploidy, some freshwater cyanobacteria contain multiple …

In many bacteria the rate of DNA replication is linked with cellular physiology to ensure that
genome duplication is coordinated with growth. Nutrient-mediated growth rate control of …

Metabolism and DNA replication are the two most fundamental biological functions in life.
The catabolic branch of metabolism breaks down nutrients to produce energy and …

Background In all living organisms, DNA replication is exquisitely regulated in a wide range
of growth conditions to achieve timely and accurate genome duplication prior to cell division …