The prognostic value of histopathology in invasive lung adenocarcinoma: a comparative review of the main proposed grading systems

S Lucà, G Zannini, F Morgillo… - Expert review of …, 2023 - Taylor & Francis
Introduction An accurate histological evaluation of invasive lung adenocarcinoma is
essential for a correct clinical and pathological definition of the tumour. Different grading …

[HTML][HTML] Novel insights into the International Association for the Study of Lung Cancer grading system for lung adenocarcinoma

KS Tan, A Reiner, K Emoto, T Eguchi, Y Takahashi… - Modern Pathology, 2024 - Elsevier
The new grading system for lung adenocarcinoma proposed by the International Association
for the Study of Lung Cancer (IASLC) defines prognostic subgroups on the basis of …

The more the micropapillary pattern in stage I lung adenocarcinoma, the worse the prognosis—a retrospective study on digitalized slides

T Zombori, T Nyári, L Tiszlavicz, R Pálföldi, E Csada… - Virchows Archiv, 2018 - Springer
Although the majority of lung adenocarcinomas show mixed pattern, only the predominant
component is taken into account according to the novel classification. We evaluated the …

Prognostic impact of histopathologic features in pulmonary invasive mucinous adenocarcinomas: proposal for a pathologic grading system

WC Chang, YZ Zhang, E Lim… - American Journal of …, 2020 - academic.oup.com
Objectives The prognostic significance of pathologic features and invasive size has not been
well studied for invasive mucinous adenocarcinoma (IMA). This study evaluates the …

Architectural grade combined with spread through air spaces (STAS) predicts recurrence and is suitable for stratifying patients who might be eligible for lung sparing …

T Zombori, A Sejben, L Tiszlavicz, G Cserni… - Pathology & Oncology …, 2020 - Springer
The spread through air spaces (STAS) has a main role in local recurrence of stage I lung
adenocarcinomas (LAs), therefore its presence might question sublobar resection as a …

Proposal of a grading system for squamous cell carcinoma of the lung—the prognostic importance of tumour budding, single cell invasion, and nuclear diameter

N Zombori-Tóth, F Hegedűs, S Almási, A Sejben… - Virchows Archiv, 2023 - Springer
The prognostic markers of lung squamous cell carcinoma (LSCC) are less investigated. The
aim of our study was to evaluate tumour budding (TB), minimal cell nest size, nuclear …

Large-cell neuroendocrine carcinoma of the lung-challenges of diagnosis and treatment

T Zombori, G Juhász-Nagy, L Tiszlavicz, G Cserni… - Orvosi …, 2020 - europepmc.org
Small-cell lung carcinoma (SCLC) and the rare large-cell neuroendocrine carcinoma belong
to the high grade pulmonary neuroendocrine carcinomas. Making the correct diagnosis and …

Development and Validation of a Nomogram for Predicting the 1-, 3-, and 5-year Survival in Patients with Acinar-predominant Lung Adenocarcinoma

Z Zuo, L Wang, K Peng, J Yang, X Li, Z Zhong… - Current Medical …, 2022 - Springer
Objective This study aimed to develop a nomogram to predict the overall survival (OS) of
patients with acinar-predominant adenocarcinoma (APA). Methods Data from patients with …

Preference of grade and lymphovascular invasion over invasive size measurement in stage I lung adenocarcinoma

H Itami, T Kawaguchi, D Yoshikawa… - Journal of Clinical …, 2023 - jcp.bmj.com
Aims Although it is necessary to measure the invasive size of lung adenocarcinoma with a
lepidic component, it is not uncommon to have trouble in measuring the invasive size of lung …

[HTML][HTML] Low-depth whole genome sequencing reveals copy number variations associated with higher pathologic grading and more aggressive subtypes of lung non …

Z Wang, L Zhang, L He, D Cui, C Liu, L Yin… - Chinese Journal of …, 2020 - ncbi.nlm.nih.gov
Objective Histology grade, subtypes and TNM stage of lung adenocarcinomas are useful
predictors of prognosis and survival. The aim of the study was to investigate the relationship …