An aberrant STAT pathway is central to COVID-19
T Matsuyama, SP Kubli, SK Yoshinaga… - Cell Death & …, 2020 - nature.com
COVID-19 is caused by SARS-CoV-2 infection and characterized by diverse clinical
symptoms. Type I interferon (IFN-I) production is impaired and severe cases lead to ARDS …
symptoms. Type I interferon (IFN-I) production is impaired and severe cases lead to ARDS …
Accessory proteins of SARS-CoV and other coronaviruses
DX Liu, TS Fung, KKL Chong, A Shukla, R Hilgenfeld - Antiviral research, 2014 - Elsevier
The huge RNA genome of SARS coronavirus comprises a number of open reading frames
that code for a total of eight accessory proteins. Although none of these are essential for …
that code for a total of eight accessory proteins. Although none of these are essential for …
Coronavirus pathogenesis
SR Weiss, JL Leibowitz - Advances in virus research, 2011 - Elsevier
Coronaviruses infect many species of animals including humans, causing acute and chronic
diseases. This review focuses primarily on the pathogenesis of murine coronavirus mouse …
diseases. This review focuses primarily on the pathogenesis of murine coronavirus mouse …
Genomic characterization of severe acute respiratory syndrome-related coronavirus in European bats and classification of coronaviruses based on partial RNA …
JF Drexler, F Gloza-Rausch, J Glende… - Journal of …, 2010 - Am Soc Microbiol
Bats may host emerging viruses, including coronaviruses (CoV). We conducted an
evaluation of CoV in rhinolophid and vespertilionid bat species common in Europe …
evaluation of CoV in rhinolophid and vespertilionid bat species common in Europe …
Understanding COVID-19 via comparative analysis of dark proteomes of SARS-CoV-2, human SARS and bat SARS-like coronaviruses
The recently emerged coronavirus designated as SARS-CoV-2 (also known as 2019 novel
coronavirus (2019-nCoV) or Wuhan coronavirus) is a causative agent of coronavirus …
coronavirus (2019-nCoV) or Wuhan coronavirus) is a causative agent of coronavirus …
MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection
J Canton, AR Fehr, R Fernandez-Delgado… - PLoS …, 2018 - journals.plos.org
Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel human coronavirus
that emerged in 2012, causing severe pneumonia and acute respiratory distress syndrome …
that emerged in 2012, causing severe pneumonia and acute respiratory distress syndrome …
A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants
A comprehensive understanding of host dependency factors for SARS-CoV-2 remains
elusive. Here, we map alterations in host lipids following SARS-CoV-2 infection using …
elusive. Here, we map alterations in host lipids following SARS-CoV-2 infection using …
The role of severe acute respiratory syndrome (SARS)-coronavirus accessory proteins in virus pathogenesis
R McBride, BC Fielding - Viruses, 2012 - mdpi.com
A respiratory disease caused by a novel coronavirus, termed the severe acute respiratory
syndrome coronavirus (SARS-CoV), was first reported in China in late 2002. The …
syndrome coronavirus (SARS-CoV), was first reported in China in late 2002. The …
Supramolecular architecture of the coronavirus particle
BW Neuman, MJ Buchmeier - Advances in virus research, 2016 - Elsevier
Coronavirus particles serve three fundamentally important functions in infection. The virion
provides the means to deliver the viral genome across the plasma membrane of a host cell …
provides the means to deliver the viral genome across the plasma membrane of a host cell …
Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells
AC Sims, SC Tilton, VD Menachery… - Journal of …, 2013 - Am Soc Microbiol
The severe acute respiratory syndrome coronavirus accessory protein ORF6 antagonizes
interferon signaling by blocking karyopherin-mediated nuclear import processes. Viral …
interferon signaling by blocking karyopherin-mediated nuclear import processes. Viral …