Redox post-translational modifications of protein thiols in brain aging and neurodegenerative conditions—focus on S-nitrosation

MJ Finelli - Frontiers in Aging Neuroscience, 2020 - frontiersin.org
Reactive oxygen species and reactive nitrogen species (RONS) are by-products of aerobic
metabolism. RONS trigger a signaling cascade that can be transduced through oxidation …

Redox regulation of autophagy in skeletal muscle

GG Rodney, R Pal, R Abo-Zahrah - Free Radical Biology and Medicine, 2016 - Elsevier
Autophagy is a cellular degradative pathway that involves the delivery of cytoplasmic
components, including proteins and organelles, to the lysosome for degradation. Autophagy …

Outer membrane vesicles secreted by pathogenic and nonpathogenic Bacteroides fragilis represent different metabolic activities

NB Zakharzhevskaya, AA Vanyushkina, IA Altukhov… - Scientific reports, 2017 - nature.com
Numerous studies are devoted to the intestinal microbiota and intercellular communication
maintaining homeostasis. In this regard, vesicles secreted by bacteria represent one of the …

Helicobacter pylori VacA induces autophagic cell death in gastric epithelial cells via the endoplasmic reticulum stress pathway

P Zhu, J Xue, Z Zhang, Y Jia, Y Tong, D Han, Q Li… - Cell death & …, 2017 - nature.com
The Helicobacter pylori vacuolating cytotoxin (VacA) can promote progressive vacuolation
and gastric injury and may be associated with human gastric cancer. Increasing evidence …

Disulfide bonds: protein folding and subcellular protein trafficking

M Narayan - The FEBS journal, 2012 - Wiley Online Library
The study of disulfide‐bond‐containing proteins has advanced our understanding of the
mechanism (s) by which the majority of secretory and membrane‐bound proteins acquire …

Diverse pathways of oxidative folding of disulfide proteins: underlying causes and folding models

JY Chang - Biochemistry, 2011 - ACS Publications
The pathway of oxidative folding of disulfide proteins exhibits a high degree of diversity,
which is manifested mainly by distinct structural heterogeneity and diverse rearrangement …

Revisiting the formation of a native disulfide bond: consequences for protein regeneration and beyond

M Narayan - Molecules, 2020 - mdpi.com
Oxidative protein folding involves the formation of disulfide bonds and the regeneration of
native structure (N) from the fully reduced and unfolded protein (R). Oxidative protein folding …

Comparative proteomic study for profiling differentially expressed proteins between C hinese left‐and right‐sided colon cancers

H Shen, J Huang, H Pei, S Zeng, Y Tao, L Shen… - Cancer …, 2013 - Wiley Online Library
The aim of the present study is to profile differentially expressed protein markers between
left‐sided colon cancer (LSCC) and right‐sided colon cancer (RSCC). Fresh tumor tissue …

Tumor interstitial fluid: proteomic determination as a possible source of biomarkers

G Baronzio, G Parmar, M Baronzio… - Cancer genomics & …, 2014 - cgp.iiarjournals.org
Tumor interstitial fluid (TIF) is formed largely by an imbalance between the forces that govern
the filtration of liquid between the luminal and abluminal parts of tumor neo-vessels. TIF is a …

Comparison of anti-cancer effects of novel protein disulphide isomerase (PDI) inhibitors in breast cancer cells characterized by high and low PDIA17 expression

A Kurpińska, J Suraj-Prażmowska, M Stojak… - Cancer Cell …, 2022 - Springer
Abstract Background Protein disulphide isomerases (PDIs) play an important role in cancer
progression. However, the relative contribution of the various isoforms of PDI in …