A guide to cell death pathways

J Yuan, D Ofengeim - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Regulated cell death mediated by dedicated molecular machines, known as programmed
cell death, plays important roles in health and disease. Apoptosis, necroptosis and …

Revisiting the role of neurotransmitters in epilepsy: An updated review

E Akyuz, AK Polat, E Eroglu, I Kullu, E Angelopoulou… - Life sciences, 2021 - Elsevier
Epilepsy is a neurologicaldisorder characterized by persistent predisposition to recurrent
seizurescaused by abnormal neuronal activity in the brain. Epileptic seizures maydevelop …

Neuroinflammation in acute ischemic and hemorrhagic stroke

DL Alsbrook, M Di Napoli, K Bhatia, J Biller… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review This review aims to provide an overview of neuroinflammation
in ischemic and hemorrhagic stroke, including recent findings on the mechanisms and …

Crosstalk between the oxidative stress and glia cells after stroke: from mechanism to therapies

G Zhu, X Wang, L Chen, C Lenahan, Z Fu… - Frontiers in …, 2022 - frontiersin.org
Stroke is the second leading cause of global death and is characterized by high rates of
mortality and disability. Oxidative stress is accompanied by other pathological processes …

Hippocampal astrocytes modulate anxiety-like behavior

WH Cho, K Noh, BH Lee, E Barcelon, SB Jun… - Nature …, 2022 - nature.com
Astrocytes can affect animal behavior by regulating tripartite synaptic transmission, yet their
influence on affective behavior remains largely unclear. Here we showed that hippocampal …

Incomplete systemic recovery and metabolic phenoreversion in post-acute-phase nonhospitalized COVID-19 patients: implications for assessment of post-acute …

E Holmes, J Wist, R Masuda, S Lodge… - Journal of proteome …, 2021 - ACS Publications
We present a multivariate metabotyping approach to assess the functional recovery of
nonhospitalized COVID-19 patients and the possible biochemical sequelae of “Post-Acute …

[HTML][HTML] Molecular mechanisms of ischemia and glutamate excitotoxicity

D Neves, IL Salazar, RD Almeida, RM Silva - Life sciences, 2023 - Elsevier
Excitotoxicity is classically defined as the neuronal damage caused by the excessive
release of glutamate, and subsequent activation of excitatory plasma membrane receptors …

Differential effects of SARS-CoV-2 variants on central nervous system cells and blood–brain barrier functions

A Proust, CJ Queval, R Harvey, L Adams… - Journal of …, 2023 - Springer
Background Although mainly causing a respiratory syndrome, numerous neurological
symptoms have been identified following of SARS-CoV-2 infection. However, how the virus …

Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination

J Hou, Y Zhou, Z Cai, M Terekhova, A Swain… - Cell reports, 2023 - cell.com
Demyelination is a hallmark of multiple sclerosis, leukoencephalopathies, cerebral
vasculopathies, and several neurodegenerative diseases. The cuprizone mouse model is …

Neuroinflammation and Parkinson's disease—From neurodegeneration to therapeutic opportunities

B Araújo, R Caridade-Silva, C Soares-Guedes… - Cells, 2022 - mdpi.com
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder
worldwide. Clinically, it is characterized by a progressive degeneration of dopaminergic …