Comparative efficacy and safety of multiple wake-promoting agents for the treatment of excessive daytime sleepiness in narcolepsy: a network meta-analysis

S Zhan, H Ye, N Li, Y Zhang, Y Cheng… - Nature and Science …, 2023 - Taylor & Francis
Purpose Narcolepsy is a rare debilitating disorder for which multiple novel pharmacological
options have been approved as treatment for the past few years. The current study …

Comparative efficacy, safety and benefit/risk of alerting agents for excessive daytime sleepiness in patients with obstructive sleep apnoea: a network meta-analysis

JL Pépin, P Lehert, RB Messaoud… - …, 2024 - thelancet.com
Background Obstructive sleep apnoea (OSA) is a common chronic respiratory disease
associated with a high burden of disabilities related to sleepiness and reduced quality of life …

Obstructive sleep apnea

LV Pham, J Jun, VY Polotsky - Handbook of clinical neurology, 2022 - Elsevier
Obstructive sleep apnea (OSA) is a disease that results from loss of upper airway muscle
tone leading to upper airway collapse during sleep in anatomically susceptible persons …

Profile of solriamfetol in the management of excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea: focus on patient selection and …

VC Abad - Nature and Science of Sleep, 2021 - Taylor & Francis
Excessive sleepiness (ES) is a symptom of obstructive sleep apnea (OSA) and narcolepsy
that has severe consequences. Wake-promoting drugs and stimulants are utilized as …

The importance of diagnosing and the clinical potential of treating obstructive sleep apnea to delay mild cognitive impairment and Alzheimer's disease: a special focus …

M Fernandes, F Placidi, NB Mercuri… - Journal of Alzheimer's …, 2021 - content.iospress.com
Obstructive sleep apnea (OSA) is a highly frequent sleep disorder in the middle-aged and
older population, and it has been associated with an increased risk of developing cognitive …

Pitolisant versus placebo for excessive daytime sleepiness in narcolepsy and obstructive sleep apnea: A meta-analysis from randomized controlled trials

J Wang, X Li, S Yang, T Wang, Z Xu, J Xu, H Gao… - Pharmacological …, 2021 - Elsevier
Excessive daytime sleepiness is considered as the prominent symptom in narcolepsy and
Obstructive Sleep Apnea (OSA). Pitolisant is a novel selective histamine H3 receptor …

Solriamfetol improves chronic sleep fragmentation-induced increases in sleep propensity and ameliorates explicit memory in male mice

C Puech, M Badran, MB Barrow, AR Runion, D Gozal - Sleep, 2023 - academic.oup.com
Obstructive sleep apnea (OSA) is a highly prevalent condition characterized by episodes of
partial or complete breath cessation during sleep that induces sleep fragmentation (SF). One …

Drugs for patients with epilepsy and excessive daytime sleepiness

G Zaccara, E Bartolini, L Tramacere, S Lattanzi - Epilepsy & Behavior, 2021 - Elsevier
Excessive daytime sleepiness (EDS) and attentional deficits are often observed in people
with epilepsy. They may be the consequence of seizures and subclinical discharges as well …

Pharmacological Treatments of Sleep–Wake Disorders: Update 2023

MS Kallweit, NP Kallweit, U Kallweit - Clinical and Translational …, 2023 - mdpi.com
Biological, environmental, behavioral, and social factors can influence sleep and lead to
sleep disorders or diseases. Sleep disorders are common, numerous, and heterogeneous in …

Sleep disorders in psychiatry

H Selsick, D O'Regan - BJPsych Advances, 2018 - cambridge.org
Sleep medicine is a truly multidisciplinary field that covers psychiatric, neurological and
respiratory conditions. As the field has developed it has become increasingly clear that there …