Notch signaling, a highly conserved pathway in mammals, is crucial for differentiation and
homeostasis of immune cells. Besides, this pathway is also directly involved in the …

Abstract Background The Notch signaling pathway is a cell signaling system that is
conserved in a variety of eukaryotes. Overall, Notch receptors and their ligands are single …

Summary Bacille Calmette-Guerin (BCG) is the only licensed vaccine against
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB) disease …

Pulmonary tuberculosis (PTB) and diabetes mellitus (DM) are common chronic diseases that
threaten human health. Patients with DM are susceptible to PTB, an important factor that …

Bone mesenchymal stem cell (BMSC)-derived exosome (BMSC-Exo) could be a treatment
method for ischemic injury. In ischemic cerebrovascular disease (IC), microglia is pivotal in …

The Notch signaling pathway is the most crucial link in the normal operation and
maintenance of physiological functions of mammalian life processes. Notch receptors …

A significant role in the pathogenesis of CAVD is played by innate immunity cells, such as
macrophages. In stenotic valves, macrophages have enhanced inflammatory activity, and …

Background Tuberculosis (TB) is a serious public health problem to human health, but the
pathogenesis of TB remains elusive. Methods To identify novel candidate genes associated …

Abstract Background The Ibizan Hound is a canine breed native to the Mediterranean
region, where leishmaniosis is an endemic zoonosis. Several studies indicate low …

Several studies have identified biomarkers for tuberculosis (TB) diagnosis based on blood
cell transcriptomics. Here, we instead studied epigenomics in the lung compartment by …