The management of type 1 diabetes in adults. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of …

RIG Holt, JH DeVries, A Hess-Fischl, IB Hirsch… - Diabetes …, 2021 - Am Diabetes Assoc
The American Diabetes Association (ADA) and the European Association for the Study of
Diabetes (EASD) convened a writing group to develop a consensus statement on the …

Monogenic diabetes

A Bonnefond, R Unnikrishnan, A Doria… - Nature Reviews …, 2023 - nature.com
Monogenic diabetes includes several clinical conditions generally characterized by early-
onset diabetes, such as neonatal diabetes, maturity-onset diabetes of the young (MODY) …

Precision medicine in diabetes: a consensus report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

WK Chung, K Erion, JC Florez, AT Hattersley… - Diabetes …, 2020 - Am Diabetes Assoc
The convergence of advances in medical science, human biology, data science, and
technology has enabled the generation of new insights into the phenotype known as …

Monogenic diabetes: a gateway to precision medicine in diabetes

H Zhang, K Colclough, AL Gloyn… - The Journal of clinical …, 2021 - Am Soc Clin Investig
Monogenic diabetes refers to diabetes mellitus (DM) caused by a mutation in a single gene
and accounts for approximately 1%–5% of diabetes. Correct diagnosis is clinically critical for …

A practical review of C-peptide testing in diabetes

E Leighton, CAR Sainsbury, GC Jones - Diabetes therapy, 2017 - Springer
C-peptide is a widely used measure of pancreatic beta cell function. It is produced in
equimolar amounts to endogenous insulin but is excreted at a more constant rate over a …

Maturity-onset diabetes of the young (MODY): current perspectives on diagnosis and treatment

T Urakami - Diabetes, metabolic syndrome and obesity: targets and …, 2019 - Taylor & Francis
Maturity-onset diabetes of the young (MODY) is characterized by autosomal dominant
inheritance, onset before 25 years of age, absence of β-cell autoimmunity, and sustained …

The clinical consequences of heterogeneity within and between different diabetes types

MJ Redondo, WA Hagopian, R Oram, AK Steck… - Diabetologia, 2020 - Springer
Advances in molecular methods and the ability to share large population-based datasets are
uncovering heterogeneity within diabetes types, and some commonalities between types …

Precision diabetes: learning from monogenic diabetes

AT Hattersley, KA Patel - Diabetologia, 2017 - Springer
The precision medicine approach of tailoring treatment to the individual characteristics of
each patient or subgroup has been a great success in monogenic diabetes subtypes, MODY …

Approach to the patient with MODY-monogenic diabetes

DT Broome, KM Pantalone, SR Kashyap… - The Journal of …, 2021 - academic.oup.com
Maturity-onset diabetes of the young, or MODY-monogenic diabetes, is a not-so-rare
collection of inherited disorders of non-autoimmune diabetes mellitus that remains …

A type 1 diabetes genetic risk score can aid discrimination between type 1 and type 2 diabetes in young adults

RA Oram, K Patel, A Hill, B Shields… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE With rising obesity, it is becoming increasingly difficult to distinguish between
type 1 diabetes (T1D) and type 2 diabetes (T2D) in young adults. There has been …