[HTML][HTML] Prognostic and predictive value of EGFR in head and neck squamous cell carcinoma

P Bossi, C Resteghini, N Paielli, L Licitra, S Pilotti… - Oncotarget, 2016 - ncbi.nlm.nih.gov
EGFR is an extensively studied biomarker in head and neck squamous cell carcinoma
(HNSCC). In this review, we discuss the prognostic and predictive role of EGFR in HNSCC …

EGFR Mutations in Head and Neck Squamous Cell Carcinoma

S Nair, JA Bonner, M Bredel - International Journal of Molecular Sciences, 2022 - mdpi.com
EGFR is a prototypical receptor tyrosine kinase that is overexpressed in multiple cancers
including head and neck squamous cell carcinoma (HNSCC). The standard of care for …

Recent advances in Oral Oncology 2007: epidemiology, aetiopathogenesis, diagnosis and prognostication

JV Bagan, C Scully - Oral oncology, 2008 - Elsevier
This paper provides a synopsis of the main papers on epidemiology, diagnosis and
prognosis of oral and oropharyngeal squamous cell carcinoma (OSCC) and head and neck …

Epidermal growth factor receptor targeted therapy of squamous cell carcinoma of the head and neck

ME Sharafinski, RL Ferris, S Ferrone… - Head & neck, 2010 - Wiley Online Library
Background Cumulative evidence implicates the epidermal growth factor receptor (EGFR)
as an important therapeutic target in head and neck squamous cell carcinoma (HNSCC) …

MicroRNA-18a attenuates DNA damage repair through suppressing the expression of ataxia telangiectasia mutated in colorectal cancer

CW Wu, YJ Dong, QY Liang, XQ He, SSM Ng… - PloS one, 2013 - journals.plos.org
Background miR-18a is one of the most up-regulated miRNAs in colorectal cancers (CRC)
based on miRNA profiling. In this study, we examined the functional significance of miR-18a …

[HTML][HTML] The challenge of blocking a wider family members of EGFR against head and neck squamous cell carcinomas

J Martinez-Useros, J Garcia-Foncillas - Oral oncology, 2015 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) represent 95% of head and neck cancer
with an incidence of over half a million people globally. The prognosis for patients with …

Genome-wide loss of heterozygosity and DNA copy number aberration in HPV-negative oral squamous cell carcinoma and their associations with disease-specific …

C Chen, Y Zhang, MM Loomis, MP Upton… - PloS one, 2015 - journals.plos.org
Oral squamous cell cancer of the oral cavity and oropharynx (OSCC) is associated with high
case-fatality. For reasons that are largely unknown, patients with the same clinical and …

[HTML][HTML] Role of EGFR gene polymorphisms in oral squamous cell carcinoma patients of Southeast Iran: A case-control study

S Saravani, N Parsamanesh… - Caspian Journal of …, 2020 - ncbi.nlm.nih.gov
Background: The decisive etiology of oral squamous cell carcinoma (OSCC) is still
ambiguous, but we recognize the contribution of genetic aberration and environmental …

Emerging perspectives in epidermal growth factor receptor targeting in head and neck cancer

S Kim, JR Grandis, A Rinaldo… - Head & Neck: Journal …, 2008 - Wiley Online Library
The epidermal growth factor receptor (EGFR) has been shown to be a promising therapeutic
target in head and neck cancer. Cetuximab, a monoclonal antibody against EGFR, has been …

Identification of epidermal growth factor receptor (EGFR) genetic variants that modify risk for head and neck squamous cell carcinoma

C Fung, P Zhou, S Joyce, K Trent, JM Yuan, JR Grandis… - Cancer letters, 2015 - Elsevier
EGFR polymorphisms have not been thoroughly evaluated for association with head and
neck squamous cell carcinoma (HNSCC) risk. We genotyped 578 HNSCC patients and 588 …