In the yeast Saccharomyces cerevisiae, Ca2+ signaling mediated by the Ca2+/calmodulin
dependent phosphatase, calcineurin, is required for survival during environmental stress …

In recent years, the emergence of fungal resistance has become frequent, partly due to the
widespread clinical use of fluconazole, which is minimally toxic and effective in the …

Calcium ions are ubiquitous intracellular messengers. An increase in the cytosolic Ca2+
concentration activates many proteins, including calmodulin and the Ca2+/calmodulin …

The calcineurin pathway is a critical signal transduction pathway in fungi that mediates
growth, morphology, stress responses, and pathogenicity. The importance of the calcineurin …

The protein phosphatase calcineurin is an important mediator connecting calcium‐
dependent signalling to various cellular responses in multiple organisms. In fungi …

Aspergillus flavus not only reduces kiwifruit production but also synthesizes carcinogenic
aflatoxins, resulting in a relevant threat to human health. p-Hydroxybenzoic acid (pHBA) is …

ABSTRACT Calcium (Ca2+) is a universal signalling molecule of life. The Ca2+ signalling is
an evolutionarily conserved process from prokaryotes to eukaryotes. Ca2+ at high …

Recently, we showed that the α subunit BCG1 of a heterotrimeric G protein is an upstream
activator of the Ca2+/calmodulin-dependent phosphatase calcineurin in the gray mold …

Ca2+-dependent signaling plays important roles in cellular development and metabolism in
fungi. Pharmacological and molecular evidence clearly indicates that Ca2+-dependent …

To investigate cation adaptation and homoeostasis in Aspergillus nidulans, two transcription-
factor-encoding genes have been characterized. The A. nidulans orthologue crzA of the …