Multi-component molecular machines are ubiquitous in biology. We review recent progress
on describing their thermodynamic properties using autonomous bipartite Markovian …

Molecular motors work collectively to transport cargo within cells, with anywhere from one to
several hundred motors towing a single cargo. For a broad class of collective-transport …

Motor-driven intracellular transport of organelles, vesicles, and other molecular cargo is a
highly collective process. An individual cargo is often pulled by a team of transport motors …

Kinesin is a microtubule-associated motor protein which works in teams to carry the cellular
cargo transport. Lipid rafts on membranous cargos reorganize, causing the motors present …

We consider the dynamics of a bio-filament under the collective drive of motor proteins. They
are attached irreversibly to a substrate and undergo stochastic attachment–detachment with …

It is often assumed in biophysical studies that when multiple identical molecular motors
interact with two parallel microtubules, the microtubules will be crosslinked and locked …

We examine the effect of cargo–motor linkage stiffness on the mechanobiological properties
of the molecular motor myosin VI. We use the programmability of DNA nanostructures to …

We study a generic one-dimensional model for an intracellular cargo driven by N motor
proteins against an external applied force. The model includes motor-cargo and motor-motor …

Dynein motors exhibit catch bonding, where the unbinding rate of the motors from
microtubule filaments decreases with increasing opposing load. The implications of this …

Cells are complex structures which require considerable amounts of organization via
transport of large intracellular cargo. While passive diffusion is often sufficiently fast for the …