Tuberculosis and lung cancer are, in many cases, correlated diseases that can be confused
because they have similar symptoms. Many meta-analyses have proven that there is a …

The rise of antimicrobial resistance has created an urgent need for antibiotic-alternative
strategies for disease control and prevention. Host defense peptides (HDPs), which have …

Antimicrobial peptides (AMPs) show great promise for clinical applications, but the utility of
naturally occurring AMPs is often limited by their stability. Here, we used a rational design …

Background Necrotic enteritis (NE) is a major enteric disease in poultry, yet effective
mitigation strategies remain elusive. Deoxycholic acid (DCA) and butyrate, two major …

Host defense peptides (HDPs) are an integral part of the innate immune system with both
antimicrobial and immunomodulatory activities. Induction of endogenous HDP synthesis is …

A novel series of quinoline-based benzamide derivatives was designed and synthesized as
histone deacetylase (HDAC) inhibitors and anticancer agents. The cytotoxic activity of the …

Host defense peptides (HDPs) are an integral part of the innate immune system acting as
the first line of defense. Modulation of HDP synthesis has emerged as a promising host …

The rising concern of antimicrobial resistance highlights a need for effective alternatives to
antibiotics for livestock production. Butyrate, forskolin, and lactose are three natural products …

Antimicrobial resistance is a major concern to public health demanding effective alternative
strategies to disease control and prevention. Modulation of endogenous host defense …

Enhancing the synthesis of endogenous host defense peptides (HDPs) has emerged as a
novel antibiotic-free approach to infectious disease control and prevention. A number of …