Smart cancer nanomedicine
Nanomedicines are extensively employed in cancer therapy. We here propose four strategic
directions to improve nanomedicine translation and exploitation.(1) Patient stratification has …
directions to improve nanomedicine translation and exploitation.(1) Patient stratification has …
Nanotechnology for COVID-19: therapeutics and vaccine research
The current global health threat by the novel coronavirus disease 2019 (COVID-19) requires
an urgent deployment of advanced therapeutic options available. The role of …
an urgent deployment of advanced therapeutic options available. The role of …
Therapeutic targeting of trained immunity
Immunotherapy is revolutionizing the treatment of diseases in which dysregulated immune
responses have an important role. However, most of the immunotherapy strategies currently …
responses have an important role. However, most of the immunotherapy strategies currently …
Brief update on endocytosis of nanomedicines
The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …
pH-responsive high stability polymeric nanoparticles for targeted delivery of anticancer therapeutics
L Palanikumar, S Al-Hosani, M Kalmouni… - Communications …, 2020 - nature.com
The practical application of nanoparticles (NPs) as chemotherapeutic drug delivery systems
is often hampered by issues such as poor circulation stability and targeting inefficiency …
is often hampered by issues such as poor circulation stability and targeting inefficiency …
[HTML][HTML] Pure drug nano-assemblies: A facile carrier-free nanoplatform for efficient cancer therapy
S Fu, G Li, W Zang, X Zhou, K Shi, Y Zhai - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Nanoparticulate drug delivery systems (Nano-DDSs) have emerged as possible solution to
the obstacles of anticancer drug delivery. However, the clinical outcomes and translation are …
the obstacles of anticancer drug delivery. However, the clinical outcomes and translation are …
[HTML][HTML] Current multistage drug delivery systems based on the tumor microenvironment
The development of traditional tumor-targeted drug delivery systems based on EPR effect
and receptor-mediated endocytosis is very challenging probably because of the biological …
and receptor-mediated endocytosis is very challenging probably because of the biological …
The blood clearance kinetics and pathway of polymeric micelles in cancer drug delivery
Polymer micelles are one of the most investigated nanocarriers for drug delivery; many have
entered clinical trials and some are in clinic use, but their delivery systems have not yet …
entered clinical trials and some are in clinic use, but their delivery systems have not yet …
Like dissolves like: A first-principles theory for predicting liquid miscibility and mixture dielectric constant
Liquid mixtures are ubiquitous. Miscibility and dielectric constant are fundamental properties
that govern the applications of liquid mixtures. However, despite their importance, miscibility …
that govern the applications of liquid mixtures. However, despite their importance, miscibility …
Application of Förster Resonance Energy Transfer (FRET) technique to elucidate intracellular and In Vivo biofate of nanomedicines
Extensive studies on nanomedicines have been conducted for drug delivery and disease
diagnosis (especially for cancer therapy). However, the intracellular and in vivo biofate of …
diagnosis (especially for cancer therapy). However, the intracellular and in vivo biofate of …