Metal (loid) s have a dual biological role as micronutrients and stress agents. A few
geochemical and natural processes can cause their release in the environment, although …

The actinomycetes are well-known bioactive natural product producers, comprising the
Streptomycetes, the richest drug-prolific family in all kingdoms, producing therapeutic …

The bacterium Myxococcus xanthus exhibits a complex multicellular life cycle. In the
presence of nutrients, cells prey cooperatively. Upon starvation, they enter a developmental …

Dramatic decrease of sugar uptake is a general phenomenon in Streptomyces at stationary
phase, when antibiotics are extensively produced. Milbemycins produced by Streptomyces …

Many biosynthetic gene clusters (BGCs) require heterologous expression to realize their
genetic potential, including silent and metagenomic BGCs. Although the engineered …

The bacterial species Streptomyces avermitilis is an important industrial producer of
avermectins, which are widely utilized as effective anthelmintic and insecticidal drugs. We …

Daptomycin produced by Streptomyces roseosporus is an important lipopeptide antibiotic
used to treat human infections caused by Gram-positive pathogenic bacteria, including drug …

Milbemycins, a group of 16-membered macrocylic lactones with excellent acaricidal,
insecticidal and anthelmintic activities, can be produced by several Streptomyces species …

Synthetic biology has boomed since the early 2000s when it started being shown that it was
possible to efficiently synthetize compounds of interest in a much more rapid and effective …

Coelimycin (CPK) producer Streptomyces coelicolor A3 (2) is a well-established model for
the genetic studies of bacteria from the genus Streptomyces, renowned for their ability to …