IL-27 Gene Therapy Ameliorates IPEX Syndrome Caused by Germline Mutation of Foxp3 Gene: A Major Role for Induction of IL-10
JQ Liu, A Jabbari, CH Lin, V Akkanapally… - The Journal of …, 2024 - journals.aai.org
Inactivating mutations of Foxp3, the master regulator of regulatory T cell development and
function, lead to immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) …
function, lead to immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) …
Interleukin-27 Promotes the Generation of Myeloid-derived Suppressor Cells to Alleviate Graft-versus-host Disease
J Zhu, L Yang, J Xia, N Zhou, J Zhu, H Zhu… - …, 2024 - journals.lww.com
Background. Stimulation of myeloid-derived suppressor cell (MDSC) formation represents a
potential curative therapeutic approach for graft-versus-host disease (GVHD), which …
potential curative therapeutic approach for graft-versus-host disease (GVHD), which …