Platelets are anucleated blood cells derived from bone marrow megakaryocytes and play a
crucial role in hemostasis and thrombosis. Platelets contain specialized storage organelles …

Neutrophils readily infiltrate infection foci, phagocytose and usually destroy microbes. In
tuberculosis (TB), a chronic pulmonary infection caused by Mycobacterium tuberculosis …

Severe acne vulgaris is a common chronic inflammatory skin disease worldwide. 5-
Aminolaevulinic acid photodynamic therapy (ALA-PDT) is effective and safe for severe acne …

Impaired lung function is common in people with a history of tuberculosis. Host-directed
therapy added to tuberculosis treatment may reduce lung damage and result in improved …

In 2019 10 million people developed symptomatic tuberculosis (TB) disease and 1.2 million
died. In active TB the inflammatory response causes tissue destruction, which leads to both …

Tuberculosis (TB) is a lethal disease and remains one of the top ten causes of mortality by
an infectious disease worldwide. It can also result in significant morbidity related to …

Background The novel coronavirus, SARS-CoV-2, has increased the burden on healthcare
systems already strained by a high incidence of tuberculosis (TB) as co-infection and dual …

Platelets play a major role in coagulation and hemostasis; evidence supports the hypothesis
that they also contribute to immunological processes. Increased platelet counts have been …

Transforming growth factor-β1 (TGFβ1) is the key profibrotic cytokine in idiopathic pulmonary
fibrosis (IPF), but the primary source of this cytokine in this disease is unknown. Platelets …

Diagnostics that more accurately detect and quantify viable Mycobacterium tuberculosis
(Mtb) in the sputum of patients undergoing therapy are needed. Current culture-and …