Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant...

[PDF] cell.comFull View

Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation

MF Orth, D Surdez, T Faehling, AC Ehlers, A Marchetto… - Cell reports, 2022 - cell.com
Ewing sarcoma (EwS) is characterized by EWSR1-ETS fusion transcription factors
converting polymorphic GGAA microsatellites (mSats) into potent neo-enhancers. Although …
被引用次数：38 相关文章 所有 12 个版本