Targeting viral proteins for restraining SARS-CoV-2: focusing lens on viral proteins beyond spike for discovering new drug targets
T Yang, SC Wang, L Ye, Y Maimaitiyiming… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Emergence of highly infectious SARS-CoV-2 variants are reducing protection
provided by current vaccines, requiring constant updates in antiviral approaches. The virus …
provided by current vaccines, requiring constant updates in antiviral approaches. The virus …
[HTML][HTML] Molecular Imaging of ACE2 Expression in Infectious Disease and Cancer
Z Li, A Hasson, L Daggumati, H Zhang, DLJ Thorek - Viruses, 2023 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2) is a cell-surface receptor that plays a critical role
in the pathogenesis of SARS-CoV-2 infection. Through the use of ligands engineered for the …
in the pathogenesis of SARS-CoV-2 infection. Through the use of ligands engineered for the …
Molecular PET/CT mapping of rhACE2 distribution and quantification in organs to aid in SARS‐CoV‐2 targeted therapy
Z Wang, C Zhao, C Li, S Liu, J Ding… - Journal of Medical …, 2023 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), which is caused by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, poses a significant threat to …
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, poses a significant threat to …
[PDF][PDF] 不同表达系统的治疗性纳米抗体研究进展
孙白荷， 吴悦， 赵芮， 楼雨馨， 李婉婷… - 中国生物工程 …, 2023 - manu60.magtech.com.cn
从骆驼科动物血清中提取的纳米抗体, 由于其具有不同于传统单克隆抗体的结构和较小的尺寸,
以及高特异性, 高理化稳定性和组织渗透性等特征, 因此显示出巨大的应用潜力 …
以及高特异性, 高理化稳定性和组织渗透性等特征, 因此显示出巨大的应用潜力 …
Preclinical Evaluation and Pilot Clinical Study of 18F-Labeled Inhibitor Peptide for Noninvasive Positron Emission Tomography Mapping of Angiotensin Converting …
J Ding, Q Zhang, J Jiang, N Zhou, Z Yu… - ACS Pharmacology & …, 2024 - ACS Publications
Angiotensin-converting enzyme 2 (ACE2) is the main molecular target for coronavirus SARS-
CoV-2 to enter cells. Molecularly specific tracers that bind to ACE2 with high affinity can be …
CoV-2 to enter cells. Molecularly specific tracers that bind to ACE2 with high affinity can be …
[HTML][HTML] Fighting the SARS-CoV-2 pandemic: focusing a new lens on COVID-19
F Wang - Research, 2022 - spj.science.org
Recent statistics regarding COVID-19, the disease caused by the SARS-CoV-2 virus, show
that the COVID-19 pandemic has had a major global impact, with the virus infecting more …
that the COVID-19 pandemic has had a major global impact, with the virus infecting more …
[PDF][PDF] Research progress of therapeutic nanobodies with different expression systems
B SUN, Y WU, R ZHAO, Y LOU, W LI… - China …, 2023 - manu60.magtech.com.cn
The nanobodies existing in the sera of camels and sharks have different structural
characteristics and molecular weight from traditional monoclonal antibodies, as well as such …
characteristics and molecular weight from traditional monoclonal antibodies, as well as such …
冠状病毒相关靶点的PET 成像研究进展
丁缙， 李大鹏， 张倩， 孟祥溪， 刘特立， 杨志， 朱华 - 药学进展, 2023 - pps.cpu.edu.cn
分子影像技术作为新兴发展的非侵入性, 活体, 动态的临床诊断技术, 是现代医疗中达到可视化和
诊疗一体化的关键技术. 其中正电子发射计算机断层扫描(PET) 以其超高的灵敏度和在核医学 …
诊疗一体化的关键技术. 其中正电子发射计算机断层扫描(PET) 以其超高的灵敏度和在核医学 …
Molecular PET/CT mapping of rhACE2 distribution and quantification in organs to aid in SARS-CoV-2 targeted therapy
H Zhu, Z Wang, C Zhao, C Li, S Liu, J Ding, C He… - Authorea …, 2023 - techrxiv.org
Objectives The aim of this study was to assess the potential of noninvasive and repeated
monitoring of rhACE2 distribution and content in organs using the ACE2-specific nuclide …
monitoring of rhACE2 distribution and content in organs using the ACE2-specific nuclide …
[引用][C] Embracing artificial intelligence design for better radiopharmaceuticals
J Tao, X Kong, Z Yang, H Zhu - iRADIOLOGY, 2024 - Wiley Online Library
Cancer has emerged as a significant threat to human life, and its incidence and mortality are
increasing rapidly. As clinicians increasingly seek to noninvasively investigate tumor …
increasing rapidly. As clinicians increasingly seek to noninvasively investigate tumor …