Modification of the Physicochemical Properties of Active Pharmaceutical Ingredients via Lyophilization

A Taldaev, DI Pankov, RP Terekhov, AK Zhevlakova… - Pharmaceutics, 2023 - mdpi.com
Bioavailability is an important biopharmaceutical characteristic of active pharmaceutical
ingredients (APIs) that is often correlated with their solubility in water. One of the methods of …

Study of chemical reactivity and molecular interactions of the hydrochlorothiazide-4-aminobenzoic acid cocrystal using spectroscopic and quantum chemical …

A Khan, N Agrawal, R Chaudhary, A Yadav… - … Acta Part A: Molecular …, 2025 - Elsevier
In this study, the molecular, electronic, and chemical properties of the drug
hydrochlorothiazide (HCTZ) are determined after cocrystallization with 4-aminobenzoic acid …

X‐Ray Crystallography and Antimicrobial Activity of Synthetic Cyanoguanidinophenytoin Cocrystals

AF Mabied, AH Moustafa, AA Abdelhamid… - …, 2024 - Wiley Online Library
A novel series of 1: 1 cocrystals of 2‐cyanoguanidinophenytoin (CNG‐DPH) with primary,
secondary, and tertiary aliphatic amines has been presented through this work. The …

Multicomponent crystal compromising dasatinib and selected co-crystals formers: a patent evaluation of EP2861589B1

R Rathi, I Singh - Pharmaceutical Patent Analyst, 2022 - Taylor & Francis
Cocrystallization has gained significant prominence in pharmaceutical product development
because of the enhancement of physical, chemical and pharmacological properties of active …

Advances in Carbamazepine Cocrystals: A Review

SS Kalantri, MD Yadav - Crystal Research and Technology, 2024 - Wiley Online Library
Carbamazepine (CBZ), a widely used antiepileptic drug, is known for its therapeutic efficacy
but exhibits suboptimal physicochemical characteristics, including limited bioavailability, low …

[PDF][PDF] Solubility and Dissolutıon Improvement of Paramethoxycinnamic Acid (PMCA) Induced by Cocrystal Formation using Caffeine as a Coformer

MI Sulistyowaty, S Fitri, N Yuliati, T Amrillah… - Sains …, 2024 - ukm.edu.my
Para-methoxy cinnamic acid (pMCA) is a derivative compound of ethyl p-methoxycinnamate
that could be obtained in nature. pMCA has excellent pharmacological properties. However …

[PDF][PDF] Pharmaceutical cocrystal-a deft technique for solubility enhancement.

S Bhattacharyya, A Manjunath - Pharmaceutical Sciences …, 2023 - pharmacy.mahidol.ac.th
Solubility enhancement of active pharmaceutical ingredients is a challenging field in the
pharmaceutical industry. Several methods and excipients are employed in the solubility …

A comprehensive review on pharmaceutical cocrystal-a subtle technique for solubility enhancement.

S Bhattacharyya, A Manjunath - Thai Journal of …, 2022 - search.ebscohost.com
Solubility enhancement of active pharmaceutical ingredients is a challenging field in the
pharmaceutical industry. Poorly soluble drugs lack oral bioavailability. Several methods and …

Minyak Kayu Putih (Eucalyptus Oil) dan Covid-19

H Husnawati - 2023 - repository.penerbiteureka.com
Semakin meningkatnya kasus COVID-19 masyarakat berupaya untuk melakukan upaya
preventif atau pencegahan. Salah satu upaya yang dilakukan untuk pencegahan COVID-19 …

Tools for the Calculation of Dissolution Experiments and their Predictive Properties

T Sakshi, K Amardeep - Software and Programming Tools in …, 2024 - benthamdirect.com
Dissolution testing, which establishes the rate and extent of the drug release from
pharmaceutical products intended for oral administration, has been recognized as a crucial …