[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Contact lens materials: a materials science perspective

CSA Musgrave, F Fang - Materials, 2019 - mdpi.com
More is demanded from ophthalmic treatments using contact lenses, which are currently
used by over 125 million people around the world. Improving the material of contact lenses …

Nano-drug delivery system targeting tumor microenvironment: a prospective strategy for melanoma treatment

M Xu, S Li - Cancer Letters, 2023 - Elsevier
Melanoma, the most aggressive form of cutaneous malignancy arising from melanocytes, is
frequently characterized by metastasis. Despite considerable progress in melanoma …

[HTML][HTML] A review on recent drug delivery systems for posterior segment of eye

K Nayak, M Misra - Biomedicine & pharmacotherapy, 2018 - Elsevier
Eye is the unique sense organ with complex and sophisticated anatomy and physiology.
Being most instrumental for vision, it is secured by varied protective barriers; ranging from …

Ocular delivery of proteins and peptides: Challenges and novel formulation approaches

A Mandal, D Pal, V Agrahari, HM Trinh… - Advanced drug delivery …, 2018 - Elsevier
The impact of proteins and peptides on the treatment of various conditions including ocular
diseases over the past few decades has been advanced by substantial breakthroughs in …

Systemic side effects of eye drops: a pharmacokinetic perspective

A Farkouh, P Frigo, M Czejka - Clinical ophthalmology, 2016 - Taylor & Francis
When administering eye drops, even when completely correctly applied, several routes of
absorption are possible and excess amounts can sometimes cause an unwanted systemic …

[HTML][HTML] Blood-brain barrier transport machineries and targeted therapy of brain diseases

J Barar, MA Rafi, MM Pourseif, Y Omidi - BioImpacts: BI, 2016 - ncbi.nlm.nih.gov
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Introduction: Desired clinical outcome of pharmacotherapy of brain diseases largely …

The use of TPGS in drug delivery systems to overcome biological barriers

MT Luiz, LD Di Filippo, RC Alves, VHS Araújo… - European Polymer …, 2021 - Elsevier
Nanotechnology has been applied in the medicine field to improve the treatment of a wide
range of diseases. However, to reach the nanomedicines delivery to desirable target tissue …

Evolution of drug-eluting biomedical implants for sustained drug delivery

JC Quarterman, SM Geary, AK Salem - European Journal of Pharmaceutics …, 2021 - Elsevier
In the field of drug delivery, the most commonly used treatments have traditionally been
systemically delivered using oral or intravenous administration. The problems associated …

Nano-based drug delivery system: recent strategies for the treatment of ocular disease and future perspective

Z Qamar, FF Qizilbash, MK Iqubal, A Ali… - Recent Patents on …, 2019 - ingentaconnect.com
The structure of the eye is very complex in nature which makes it a challenging task for
pharmaceutical researchers to deliver the drug at the desired sites via different routes of …